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Table 2 Metabolic measures at 5-year follow-up, during fasting and 2-h OGTT, after 75 g glucose overload

From: Evolution of metabolic alterations 5 Years after early puberty in a cohort of girls predisposed to polycystic ovary syndrome

 

Controls (n = 8)

PCOSr (n = 8)

 

Fasting

2 h

Fasting

2 h

Glucose (mmol/l)

5.0 (4.6–5.3)

5.7 (5.1–7.3)

4.6 (4.4–4.8)

5.8 (5.3–6.8)

Insulin (pmol/l)

70 (38–109)

290 (114–506)

65 (32–75)

361 (239–643)

NEFA (μEq/L)

395 (234–616)

25 (17–41)

582 (391–661)

11 (4–14)a

Triglycerides (mmol/l)

1.2 (0.7–1.6)

-

0.7 (0.6–0.9)

-

Total adiponectin (mg/l)

9.8 (6.9–12.2)

10.4 (6.9–13.6)

10.7 (8.5–15.4)

11.8 (8.7–15.7)

Leptin (μg/l)

8.4 (2.9–14.3)

7.5 (2.5–17.6)

8.6 (4.4–15.4)

6.1 (3.6–21.6)

  1. Values are expressed as median (25th–75th percentiles) and compared between groups with Mann-Whitney test
  2. aSignificant difference between groups, p value = 0.003
  3. To convert values for glucose to mg/dL, multiply by 18; for insulin to μU/mL, multiply by 0.17; for triglycerides to mg/dL, multiply by 88.50
  4. NEFA Non-esterified fatty acids
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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