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Table 3 Hypothetical intention-to-treat cumulative outcomes

From: Towards a better understanding of preimplantation genetic screening for aneuploidy: insights from a virtual trial for women under the age of 40 when transferring embryos one at a time

1000 virtual women started Fresh FET1 FET2 FET3 FET4 FET5 FET6 FET7 FET8 FET9
Not-tested cycles (n) 1000 596 362 199 102 48 25 13 2 1
 Not-tested transfer attempts (n) 870 593 355 197 100 48 25 13 2 1
 Clinical miscarriages (n) 27 14 6 8 0 0 1 0 0 0
  CCMR (%) 2.7 4.1 4.7 5.5 5.5 5.5 5.6 5.6 5.6 5.6
 Live birth events (n) 244 170 121 59 26 14 6 7 0 1
  CLBR (%) 24.4 41.4 53.5 59.4 62.0 63.4 64.0 64.7 64.7 64.8
PGS1 cycles (n) 1000 440 189 66 21 10 3 1 0 0
 PGS1 transfer attempts (n) 841 434 186 64 21 10 3 1 0 0
 Clinical miscarriages (n) 27 7 2 0 1 0 0 0 0 0
  CCMR (%) 2.7 3.4 3.6 3.6 3.7 3.7 3.7 3.7 3.7 3.7
 Live birth events (n) 335 174 78 30 7 6 2 1 0 0
  CLBR (%) 33.5 50.9 58.7 61.7 62.4 63.0 63.2 63.3 63.3 63.3
PGS2 cycles (n) 1000 502 261 140 59 29 14 6 1 0
 PGS2 transfer attempts (n) 870 500 255 138 58 28 14 6 1 0
 Clinical miscarriages (n) 27 10 2 5 1 0 0 1 0 0
  CCMR (%) 2.7 3.7 3.9 4.4 4.5 4.5 4.5 4.6 4.6 4.6
 Live birth events (n) 336a 176 85 35 7 6 2 1 0 0
  CLBR (%) 33.6 51.2 59.7 63.2 63.9 64.5 64.7 64.8 64.8 64.8
PGS3 cycles (n) 1000 0 0 0 0 0 0 0 0 0
 PGS3 transfer attempts (n) 652 0 0 0 0 0 0 0 0 0
 Clinical miscarriages (n) 0 0 0 0 0 0 0 0 0 0
  CCMR (%) 0 0 0 0 0 0 0 0 0 0
 Live birth events (n) 652 0 0 0 0 0 0 0 0 0
  CLBR (%) 65.2 65.2 65.2 65.2 65.2 65.2 65.2 65.2 65.2 65.2
  1. aIncludes a live birth event from a cohort comprising one embryo which had a false abnormal test result