Table 3 Hypothetical intention-to-treat cumulative outcomes
1000 virtual women started | Fresh | FET1 | FET2 | FET3 | FET4 | FET5 | FET6 | FET7 | FET8 | FET9 |
|---|---|---|---|---|---|---|---|---|---|---|
Not-tested cycles (n) | 1000 | 596 | 362 | 199 | 102 | 48 | 25 | 13 | 2 | 1 |
Not-tested transfer attempts (n) | 870 | 593 | 355 | 197 | 100 | 48 | 25 | 13 | 2 | 1 |
Clinical miscarriages (n) | 27 | 14 | 6 | 8 | 0 | 0 | 1 | 0 | 0 | 0 |
CCMR (%) | 2.7 | 4.1 | 4.7 | 5.5 | 5.5 | 5.5 | 5.6 | 5.6 | 5.6 | 5.6 |
Live birth events (n) | 244 | 170 | 121 | 59 | 26 | 14 | 6 | 7 | 0 | 1 |
CLBR (%) | 24.4 | 41.4 | 53.5 | 59.4 | 62.0 | 63.4 | 64.0 | 64.7 | 64.7 | 64.8 |
PGS1 cycles (n) | 1000 | 440 | 189 | 66 | 21 | 10 | 3 | 1 | 0 | 0 |
PGS1 transfer attempts (n) | 841 | 434 | 186 | 64 | 21 | 10 | 3 | 1 | 0 | 0 |
Clinical miscarriages (n) | 27 | 7 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
CCMR (%) | 2.7 | 3.4 | 3.6 | 3.6 | 3.7 | 3.7 | 3.7 | 3.7 | 3.7 | 3.7 |
Live birth events (n) | 335 | 174 | 78 | 30 | 7 | 6 | 2 | 1 | 0 | 0 |
CLBR (%) | 33.5 | 50.9 | 58.7 | 61.7 | 62.4 | 63.0 | 63.2 | 63.3 | 63.3 | 63.3 |
PGS2 cycles (n) | 1000 | 502 | 261 | 140 | 59 | 29 | 14 | 6 | 1 | 0 |
PGS2 transfer attempts (n) | 870 | 500 | 255 | 138 | 58 | 28 | 14 | 6 | 1 | 0 |
Clinical miscarriages (n) | 27 | 10 | 2 | 5 | 1 | 0 | 0 | 1 | 0 | 0 |
CCMR (%) | 2.7 | 3.7 | 3.9 | 4.4 | 4.5 | 4.5 | 4.5 | 4.6 | 4.6 | 4.6 |
Live birth events (n) | 336a | 176 | 85 | 35 | 7 | 6 | 2 | 1 | 0 | 0 |
CLBR (%) | 33.6 | 51.2 | 59.7 | 63.2 | 63.9 | 64.5 | 64.7 | 64.8 | 64.8 | 64.8 |
PGS3 cycles (n) | 1000 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PGS3 transfer attempts (n) | 652 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical miscarriages (n) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CCMR (%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Live birth events (n) | 652 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CLBR (%) | 65.2 | 65.2 | 65.2 | 65.2 | 65.2 | 65.2 | 65.2 | 65.2 | 65.2 | 65.2 |