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Table 2 Baseline characteristics and IVF outcomes in women serum TSH concentration did and did not exceed 2.5 mIU/L before the IVF cycle

From: Outcome of in vitro fertilization in women with subclinical hypothyroidism

Characteristics TSH ≥ 2.5mIU/L TSH < 2.5mIU/L P
n = 62 n = 114  
Age (yrs) 30.48 ± 4.07 29.56 ± 4.37 0.336
BMI(kg/m2) 23.60 ± 4.05 22.29 ± 3.18 0.099
Previous pregnancies 48.4% 54.4%  
AFC 12.00 ± 5.00 12.00 ± 8.00 0.972
TSH(mIU/L) 2.60,4.21 0.32,1.88 0.0
FT3(pmol/L) 4.73 ± 0.76 5.10 ± 0.99 0.005
FT4(pmol/L) 17.29 ± 2.29 20.10 ± 3.99 0.001
Indication to IVF    0.439
Tubal factor infertility 45.2% 52.6%  
Ovulatory dysfunction 6.4% 8.8%  
Endometriosis 3.2% 0%  
Male 12.9% 17.5%  
Mixed 25.8% 19.3%  
Unexplained infertility 6.5% 1.8%  
Protocol of stimulation    
Long protocol 77.4% 89.5%  
Short protocol 6.5% 3.5%  
GnRH antagonists 3.2% 0%  
ART procedure    0.8
IVF 75.8% 70.2%  
ICSI 24.2% 29.8%  
Duration of stimulation(Days) 11.23 ± 1.82 11.98 ± 2.09 0.106
Total amount of recombinant FSH administration 2025 ± 825 2475.00 ± 1350.00 0.128
Serum estradiol at HCG Administration(pg/ml) 1983.50 ± 2079 2529.00 ± 2005.00 0.108
Total number of oocytes retrieved 10.00 ± 8.00 11.00 ± 8.00 0.752
Total number of good quality embryos 2.00 ± 3.00 4.00 ± 6.00 0.767
Clinical pregnancies 38.7% 47.4% 0.436
Miscarriages 16.7% 7.4% 0.379
Live birth rate 32.3% 43.9% 0.288
  1. Data are reported as %,mean ± standard deviation or quartile,as appropriate
  2. AFC antral follicle, BMI, body mass index, FSH follicle-stimulating hormone, GnRH gonadotropin-releasing hormone