Table 2 Baseline characteristics and IVF outcomes in women serum TSH concentration did and did not exceed 2.5 mIU/L before the IVF cycle
From: Outcome of in vitro fertilization in women with subclinical hypothyroidism
Characteristics | TSH ≥ 2.5mIU/L | TSH < 2.5mIU/L | P |
|---|---|---|---|
n = 62 | n = 114 | ||
Age (yrs) | 30.48 ± 4.07 | 29.56 ± 4.37 | 0.336 |
BMI(kg/m2) | 23.60 ± 4.05 | 22.29 ± 3.18 | 0.099 |
Previous pregnancies | 48.4% | 54.4% | |
AFC | 12.00 ± 5.00 | 12.00 ± 8.00 | 0.972 |
TSH(mIU/L) | 2.60,4.21 | 0.32,1.88 | 0.0 |
FT3(pmol/L) | 4.73 ± 0.76 | 5.10 ± 0.99 | 0.005 |
FT4(pmol/L) | 17.29 ± 2.29 | 20.10 ± 3.99 | 0.001 |
Indication to IVF | 0.439 | ||
Tubal factor infertility | 45.2% | 52.6% | |
Ovulatory dysfunction | 6.4% | 8.8% | |
Endometriosis | 3.2% | 0% | |
Male | 12.9% | 17.5% | |
Mixed | 25.8% | 19.3% | |
Unexplained infertility | 6.5% | 1.8% | |
Protocol of stimulation | |||
Long protocol | 77.4% | 89.5% | |
Short protocol | 6.5% | 3.5% | |
GnRH antagonists | 3.2% | 0% | |
ART procedure | 0.8 | ||
IVF | 75.8% | 70.2% | |
ICSI | 24.2% | 29.8% | |
Duration of stimulation(Days) | 11.23 ± 1.82 | 11.98 ± 2.09 | 0.106 |
Total amount of recombinant FSH administration | 2025 ± 825 | 2475.00 ± 1350.00 | 0.128 |
Serum estradiol at HCG Administration(pg/ml) | 1983.50 ± 2079 | 2529.00 ± 2005.00 | 0.108 |
Total number of oocytes retrieved | 10.00 ± 8.00 | 11.00 ± 8.00 | 0.752 |
Total number of good quality embryos | 2.00 ± 3.00 | 4.00 ± 6.00 | 0.767 |
Clinical pregnancies | 38.7% | 47.4% | 0.436 |
Miscarriages | 16.7% | 7.4% | 0.379 |
Live birth rate | 32.3% | 43.9% | 0.288 |