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Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use

Fig. 1

Schematics of PGS. The currently in use PGS procedure (PGS 2.0) is based on a single TEB of on average approximately 6 cells, which is alleged to accurately reflect the chromosomal status of the developing embryo/fetus. The procedure has entered worldwide clinical use without prior clinical validation. Three crucial questions (unresolved issues in the figure) still require resolution. This manuscript attempts to answer the first of these questions, whether a single TEB accurately enough reflects the whole TE to discriminate between embryos that can undergo transfer and those that should be discarded

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