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Table 4 Increasing the accuracy of genetic diagnosis following selection of additional donors

From: Improving preimplantation genetic diagnosis (PGD) reliability by selection of sperm donor with the most informative haplotype

  First chosen donor Total no. of additional tested donors Newly selected donor
Subject No. No. of informative markers Misdiagnosis risk No. of informative markers Misdiagnosis risk
 #6 4 0.05% in female offspring 3 5 0.10%
 #7 1 15% in female offspring 4 5 0.10%
 #12 1 15% 4 3 1.56%
 #13 1 15% 5 3 1.56%
 #14 3 0.34% 8 5 0.10%
 #15 2 2.25% 2 6 0.02%
 #16 3 0.34% 4 4 0.39%
 #17 4 0.0506% 4 9 0.0004%
Average ± SEM 2.38 ± 1.30 6.00% ±7.48 4.25 ± 1.75 5.00 ± 1.93 0.48% ±0.68