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Table 2 Comparison of number of informative polymorphic markers before and after donors’ contribution

From: Improving preimplantation genetic diagnosis (PGD) reliability by selection of sperm donor with the most informative haplotype

Patient # Inheritance pattern No. of informative markers in patient No. of informative markers following donor contribution
 1 X-linked 4 4
 2 X-linked 5 3
 3 X-linked 6 3
 4 X-linked 7 5
 5 X-linked 6 2
 6 X-linked 8 4
 7 X-linked 6 1
 8 Auto. dom. 5 2
 9 Auto. dom. 5 2
 10 Auto. dom. 5 5
 11 Auto. dom. 4 2
 12 Auto. dom. 3 1
 13 Auto. dom 5 1
 14 Auto. dom. 9 3
 15 Auto. dom. 6 2
 16 Auto. dom. 6 3
 17 Auto. dom. 9 4
Average number of informative markers   5.82 ± 1.67 2.76 ± ±1.30
  1. Auto. dom. = autosomal dominant
  2. The influence of the donor in X-linked disorders is relevant only for female embryos, since male embryos inherit Y paternal chromosome