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Table 2 Comparison of number of informative polymorphic markers before and after donors’ contribution

From: Improving preimplantation genetic diagnosis (PGD) reliability by selection of sperm donor with the most informative haplotype

Patient #

Inheritance pattern

No. of informative markers in patient

No. of informative markers following donor contribution

 1

X-linked

4

4

 2

X-linked

5

3

 3

X-linked

6

3

 4

X-linked

7

5

 5

X-linked

6

2

 6

X-linked

8

4

 7

X-linked

6

1

 8

Auto. dom.

5

2

 9

Auto. dom.

5

2

 10

Auto. dom.

5

5

 11

Auto. dom.

4

2

 12

Auto. dom.

3

1

 13

Auto. dom

5

1

 14

Auto. dom.

9

3

 15

Auto. dom.

6

2

 16

Auto. dom.

6

3

 17

Auto. dom.

9

4

Average number of informative markers

 

5.82 ± 1.67

2.76 ± ±1.30

  1. Auto. dom. = autosomal dominant
  2. The influence of the donor in X-linked disorders is relevant only for female embryos, since male embryos inherit Y paternal chromosome