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Fig. 6 | Reproductive Biology and Endocrinology

Fig. 6

From: Human LH and hCG stimulate differently the early signalling pathways but result in equal testosterone synthesis in mouse Leydig cells in vitro

Fig. 6

Evaluation of testosterone production upon LH or hCG stimulation in the presence or absence of specific inhibitors, in mouse Leydig cells. The cells were stimulated 24 h by EC80 LH and hCG, in the presence or absence of H-89 or U0126. Total testosterone levels were measured by immune-assay and represented as means ± SEM (§ = significant vs “unstimulated, no inhibitors”; * = significant LH/hCG vs corresponding LH/hCG samples without inhibitor; Mann-Whitney’s U-test; P < 0.05; n = 4)

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