Table 4 Comparison of microarray data from GC cultured under high vs. normal density conditions in vitro and before and after the pre-ovulatory LH surge in vivo
Gene symbol | Gene title | FC in vitro | FC in vivo | corr. r | p-value |
|---|---|---|---|---|---|
P4HA3 | prolyl 4-hydroxylase, alpha polypeptide III | 1.7 | 75.8 | 0.997 | 0.00001 |
ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 1.9 | 7.2 | 0.995 | 0.00004 |
WWC2 | WW and C2 domain containing 2 | 1.5 | 3.9 | 0.995 | 0.00004 |
TACC3 | transforming, acidic coiled-coil containing protein 3 | −1.7 | −5.4 | 0.995 | 0.00004 |
ATAD2 | ATPase family, AAA domain containing 2 | −1.8 | −8.1 | 0.994 | 0.00005 |
INHBA | inhibin, beta A | −2.4 | −29.5 | 0.994 | 0.00005 |
CAPG | capping protein (actin filament), gelsolin-like | 1.7 | 7.3 | 0.994 | 0.00005 |
LOC784007 | uncharacterized LOC784007; SLAM family member 9-like | −2.0 | −21.8 | 0.993 | 0.00007 |
ITPKA | inositol-trisphosphate 3-kinase A | 2.2 | 6.7 | 0.993 | 0.00007 |
QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 1.6 | 5.4 | 0.992 | 0.00009 |
NDRG1 | N-myc downstream regulated 1 | 4.3 | 63.8 | 0.992 | 0.00010 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 | 1.6 | 15.0 | 0.991 | 0.00013 |
CDCA3 | cell division cycle associated 3 | −1.6 | −11.0 | 0.989 | 0.00017 |
RGS2 | regulator of G-protein signaling 2, 24 kDa | 3.3 | 194.0 | 0.989 | 0.00020 |
HEG1 | HEG homolog 1 (zebrafish) | −2.1 | −29.7 | 0.985 | 0.00035 |
PTX3 | pentraxin 3, long | 3.0 | 643.9 | 0.958 | 0.00257 |
SRGN | serglycin | −4.1 | −29.9 | 0.924 | 0.00841 |
ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 1.9 | 28.5 | 0.967 | 0.00166 |
CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 | −7.0 | −397.6 | 0.912 | 0.01140 |
HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 2.4 | 14.5 | 0.898 | 0.01493 |
FSHR | follicle stimulating hormone receptor | −4.6 | −4.1 | 0.896 | 0.01555 |
LHCGR | luteinizing hormone/choriogonadotropin receptor | −2.4 | −7.9 | 0.811 | 0.05005 |
AHSG | alpha-2-HS-glycoprotein | 36.6 | 152.3 | 0.809 | 0.05110 |
VNN2 | vanin 2 | 5.9 | 116.0 | 0.749 | 0.08659 |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 9.6 | 24.4 | 0.718 | 0.10777 |