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Table 1 Results from early/later platelet depletion experiment. All results were based on multiple regression analyses with the independent variable square-root transformed and dummy variables indicating the presence or absence of adenomyosis, non-immune IgG antibody injection or not, the dosage of antibody to deplete platelets and the dosage of Ozagrel as co-variables

From: Anti-platelet therapy holds promises in treating adenomyosis: experimental evidence

Name

Induction of adenomyosis

Ozagrel treatment

Platelet depletion

R 2

Extent of CD41+ platelet aggregation

↑

***

↓

***

↓

***

0.54

Number of infiltrated F4/80+ macrophages

↑

***

↓

**

↓

*

0.30

Phosph-p65

↑

***

↓

**

↓

**

0.31

PR-B

↓

***

↑

***

↑

***

0.73

COX-2

↑

***

↓

***

↓

***

0.48

TRPV1

↑

***

↓

***

↓

***

0.47

OTR

↑

***

↓

***

↓

***

0.58

Collagen I

↑

***

↓

***

↓

*

0.29

Collagen IV

↑

***

↓

**

↓

***

0.33

Myometrial OTR

↑

***

↓

***

↓

***

0.77

  1. ↓: Denotes that the immunoreactivity to this protein at hand was significantly decreased based on multiple linear regression analysis;↑Denotes that the immunoreactivity to this protein of interest was significantly increased based on multiple linear regression analysis. The R 2 value of the corresponding regression model is shown at the right-most column. Symbols of statistical significance levels: *: p<0.05; **: p<0.01; ***: p<0.001