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Table 1 Characteristics of studies included in the meta-analysis

From: Which one has a better obstetric and perinatal outcome in singleton pregnancy, IVF/ICSI or FET?: a systematic review and meta-analysis

Study Area/duration Type of study Population Embryo transferred Freezing techniques FET protocol Measurements assessed
Fresh ET FET
1994 Wada UK 1985–1991 Retro IVF vs. FET D2/D3 embryos Cleavage embryos/blastocysts Slow freezing Natural/HRT cycles Preterm birth LBW Still birth
2005 Wang Australia 1996–2000 Retro IVF/ICSI/GIFT vs. FET Not mentioned Not mentioned Not mentioned Not mentioned Preterm birth LBW
2008 Belva Belgium 1983–2006 Retro IVF/ICSI vs. FET D1,2,3,5 embryo D1/2/3/5 embryo A slow controlled-rate freezing procedure Natural cycles/stimulated cycles Preterm birth LBW
2008 Shih Australia 1978–2005 Retro IVF/ICSI/GIFT vs. FET D2/D3 embryo D2/D3 embryo No specific description Natural/artificial cycles Preterm birth LBW Perinatal mortality Cesarean section
2010 Aflatoonian Iran 2006–2008 Retro IVF/ICSI vs. FET D2/D3 embryo D2/D3 embryo Vitrification Artificial cycles Preterm birth LBW
2010 Pelkonen Finland 1995–2006 Cohort study IVF/ICSI vs. FET D2/D3 embryo D2/D3 embryo Slow freezing Natural/artificial cycles Preterm birth LBW Still birth Perinatal mortality Cesarean section
2010 Pinborg Denmark 1995–2007 Cohort study IVF/ICSI vs. FET D2/D3 embryo D2/D3 embryo Slow freezing Not mentioned Preterm birth LBW Still birth Perinatal mortality Cesarean section
2010 Wikland Sweden 2006–2008 Cohort study IVF/ICSI vs. FET blastocysts D2/D3 embryo/blastocysts Vitrification/slow-freezing Natural/artificial/stimulated cycles Preterm birth LBW Perinatal mortality Cesarean section
2011 Henningsen Denmark 1994–2006 Cohort study IVF/ICSI vs. FET D2 embryo D2 embryo Slow-freezing Not mentioned LBW
2012 Kalra United States 2004–2006 Cohort study IVF vs. FET Not mentioned Not mentioned Not mentioned Not mentioned Preterm birth LBW
2012 Kato Tokyo 2006–2008 Retro IVF/ICSI vs. FET Cleavage stage embryo/blastocyst Cleavage stage embryo/ blastocyst Vitrification Natural/artificial cycles Preterm birth LBW Still birth Perinatal mortality
2013 Wennerholm Denmark −2007 Retro IVF/ICSI vs. FET D2 embryo D2 embryo Slow-freezing Not mentioned Preterm birth LBW Still birth Perinatal mortality Cesarean section
2015 Kemal Antalya 2012–2012 Retro IVF vs. FET Blastocyst Blastocyst Vitrification Artificial cycles Still birth
  1. Abbreviation: Retro retrospective