Fig. 1
Detection of toxicity by two mouse embryo culture methods. To determine sensitivity of two culture methods—micro-drop (red) or micro-well (black), adulterated media containing formaldehyde (from 1 to 7× concentrated, where 1 × = 9.3 × 10−5%) were used in parallel to culture fresh one-cell mouse embryos (B6D2F1 × B6C3F1). Development of mouse embryos was monitored by morphology at 96 h after uninterrupted culture for % blastocyst rates (including expanded and hatching/hatched, n = 33)