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Table 2 Univariate analysis of patient, treatment and outcome parameters

From: Ectopic pregnancy risk factors for ART patients undergoing the GnRH antagonist protocol: a retrospective study

 

Outcome

P-value

OR [95 % CI]

 

IUP (N = 359)

EP (N = 21)

Age (years)

30.93 ± 5.8 [31]

30.74 ± 5.26 [32]

0.7346

0.99 [0.92–1.06]

Duration (years)

2.97 ± 2.43 [2]

3.23 ± 2.39 [2.5]

0.6894

1.03 [0.89–1.2]

BMI (kg/m2)

26.68 ± 20.08 [24.61]

25.05 ± 4.94 [22.41]

0.6499

0.98 [0.9–1.07]

FSH (IU/L)

6.96 ± 2.52 [6.59]

6.97 ± 2.62 [6.08]

0.9736

1.003 [0.84–1.19]

Parity

0.47 ± 0.68 [0]

0.62 ± 0.59 [1]

0.3497

1.25 [0.78–1.98]

Prior CS

38 (10.58)

6 (28.57)

0.0275

3.37 [1.14–9.91]

Male factor infertility

244 (67.97)

10 (47.62)

0.0854

0.45 [0.18–1.12]

Endometriosis

11 (3.06)

3 (14.29)

0.0199

4.89 [1.29–18.6]

Mechanical factor

53 (14.76)

8 (38.1)

0.0129

3.53 [1.31–9.53]

Unexplained

46 (12.81)

4 (19.05)

0.4282

1.56 [0.52–4.67]

PCOS

61 (16.99)

3 (14.29)

0.8444

0.88 [0.26–3.01]

IVF insemination

114 (32.02)

15 (71.43)

0.001

5.19 [1.95–13.83]

ICSI insemination

242 (67.98)

6 (28.57)

 

1

Total FSH dose (IU)

1865.72 ± 938.57 [1675]

2170.24 ± 931.52 [2250]

0.0889

1.03 [0.99–1.08]a

LH included in stimulation

131 (36.49)

9 (42.86)

0.6775

1.19 [0.52–2.73]

Stimulation days

8.75 ± 1.84 [9]

9.48 ± 1.81 [9]

0.0273

1.21 [1.02–1.44]

Estradiol (pg/mL)

1470.73 ± 778.02 [1336.4]

2112.88 ± 1302.22 [1679.7]

0.0134

1.08 [1.02–1.14]a,b

Progesterone (ng/mL)

0.9 ± 0.4 [0.8]

1.14 ± 0.4 [1.08]

0.0116

2.85 [1.26–6.45]b

Endometrial Thickness (mm)

10.25 ± 2.29 [10]

9.22 ± 2.42 [9]

0.0965

0.8 [0.61–1.04] b,c

GnRH agonist trigger

49 (13.65)

11 (52.38)

<.0001

7.55 [3.01–18.96]

r-HCG trigger

310 (86.35)

10 (47.62)

 

1

Number of oocytes aspirated

8.5 ± 4.97 [8]

12.67 ± 6.62 [11]

0.0033

1.13 [1.04–1.22]

Number of embryos transferred

1.93 ± 0.63 [2]

1.86 ± 0.48 [2]

0.3385

0.72 [0.36–1.42]

  1. Categorical variables are presented as frequencies and percentages. Continuous variables are presented with mean ± standard deviation and [median]
  2. aCalculated per 100 unit increase, badjusted for day measured relative to the day of ovulation trigger (see text), cCalculated per 5 mm increase