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Table 1 Diameter of the seminiferous tubules, the area occupied by Leydig cells and the number of Leydig cells per unit area of interstitial tissue in control and flutamide-exposed rats

From: Flutamide induces alterations in the cell-cell junction ultrastructure and reduces the expression of Cx43 at the blood-testis barrier with no disturbance in the rat seminiferous tubule morphology

  Control Flutamide-treated
Diameter of the seminiferous tubules (μm) 287.80 ± 32.09 295.11 ± 35.98
The area occupied by Leydig cells per 40 fields of vision (mm2) 3.42 ± 0.11 5.18 ± 0.28*
The number of Leydig cells per 1 mm2 of interstitial tissue 5984.87 ± 905.91 3275.30 ± 390.41**
  1. Data are expressed as means ± SD. Significant differences from control values are denoted as * p < 0.05 and ** p < 0.05 (n = 6 animals/each group)