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Table 3 Effects of chemical lesion of the DRN or MRN raphe nuclei on hormonal concentrations (Mean ± S.E.M.)

From: Dorsal and medial raphe nuclei participate differentially in reproductive functions of the male rat

Age at sacrifice Group n FSH
(ng/ml of serum)
LH
(ng/ml of serum)
Progesterone
(ng/ml of serum)
Testosterone
(ng/ml of serum)
45 Days
  Control 16 10.1 ± 0.66 0.57 ± 0.06 16.6 ± 1.9 0.97 ± 0.14
  Sham DRN 20 8.7 ± 0.30 0.37 ± 0.05 12.5 ± 0.91 0.68 ± 0.10
  Lesion DRN 14 5.9 ± 0.87a,b 0.33 ± 0.06 10.8 ± 1.2 0.65 ± 0.09
  Sham MRN 11 9.6 ± 0.35 0.68 ± 0.06 12.4 ± 2.1 0.82 ± 0.17
  Lesion MRN 10 8.6 ± 0.56 0.59 ± 0.08 9.2 ± 2.9 0.97 ± 0.15
65 Days
  Control 22 8.7 ± 0.38 0.58 ± 0.03 8.0 ± 1.1 2.43 ± 0.24
  Sham DRN 20 8.2 ± 0.30 0.60 ± 0.04 9.5 ± 1.3 2.47 ± 0.11
  Lesion DRN 22 5.4 ± 0.35a,b 0.42 ± 0.07 7.6 ± 1.5 1.71 ± 0.11
  Sham MRN 10 6.1 ± 0.38 0.75 ± 0.05 4.6 ± 0.8 2.40 ± 0.37
  Lesion MRN 15 6.3 ± 0.28 0.75 ± 0.03 4.2 ± 0.5 1.54 ± 0.31
  1. Mean ± s.e.m; Sham; sham operation; DRN, dorsal raphe nucleus; MRN, medial raphe nucleus
  2. a p < 0.05 vs. Control group (two-way ANOVA followed by Tukey's test)
  3. b p < 0.05 vs. Sham DRN (two-way ANOVA followed by Tukey's test)