Parturition dysfunction in obesity: time to target the pathobiology

Table 1 Obese women demonstrate abnormally slow cervical dilation in first stage labor

Number previous vaginal births	Study	BMI <25.0	BMI 25.0-29.9	BMI 30.0-34.9	BMI 35.0-39.9	BMI ≥40	p value
Zero	Kominiarek et al., 2011 [19]
	Median	5.4 hrs	5.7 hrs	6.0 hrs	6.7 hrs	7.7 hrs	<0.0001
	(95 % ile)	(18.2 hrs)	(18.8 hrs)	(19.9 hrs)	(22.2 hrs)	(25.6 hrs)	<0.0001
	Norman et al., 2012 [20]
	Median	4.6 hrs	5.0 hrs	5.5 hrs		6.7 hrs	<0.01
	(95 % ile)	(14.4 hrs)	(15.7 hrs)	(17.3 hrs)		(21.2 hrs)	<0.01
One	Kominiarek et al., 2011 [19]
	Median	4.6 hrs	4.5 hrs	4.7 hrs	5.0 hrs	5.4 hrs	<0.0001
	(95 % ile)	(17.5 hrs)	(17.4 hrs)	(17.9 hrs)	(19.0 hrs)	(20.6 hrs)	<0.0001
	Norman et al., 2012 [20]
	Median	3.3 hrs	3.9 hrs	4.3 hrs		5.0 hrs	<0.01
	(95 % ile)	(12.6 hrs)	(15.1 hrs)	(16.5 hrs)		(19.2 hrs)	<0.01

Adjusted duration of labor from 4–10 centimeters cervical dilation by BMI at the time of delivery. Data are median and 95%ile hours in labor
Kominiarek’s median duration adjusted for age, height, race, gestational age, diabetes, induction, augmentation, epidural (first stage), operative vaginal delivery, and birthweight (N = 118,978)
Norman’s median duration adjusted for induction, race, birth weight > 4,000 g (N = 5,204)

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