Skip to main content
Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Decidualisation of human endometrial stromal cells is associated with increased expression and secretion of prorenin

Fig. 3

Effects on the expression of genes and proteins known to be responsive to stimulation by the prorenin receptor/prorenin angiotensin system. a and c Relative mRNA abundance of PAI-1 (SERPINE1) and its protein. Both E2 + MPA alone treatment and MPA-mix treatment stimulated expression of PAI-1(SERPINE1) in HESCs (P < 0.001). AZA had no effect. b and d MPA-mix treatment stimulated the expression of VEGF Aand its protein compared with all other treatments (all P < 0.001). Different superscripts denote differences between groups. CON, treated with vehicle alone; E2 + MPA, treatment with 10 nM 17β-estradiol (E2) and 1 μM medroxyprogesterone acetate (MPA); E2 + MPA + cAMP, E2 + MPA + cAMP, treatment as for E2 + MPA plus 0.5 mM cAMP

Back to article page

Reproductive Biology and Endocrinology

ISSN: 1477-7827

Contact us