Parameter | Ratio of XM17:Gonal-f®
| 90 % CI |
---|
AUC(0-t)
| 1.028 | (0.931, 1.134) |
Cmax
| 1.017 | (0.958, 1.080) |
AUC(0-168h)
| 1.025 | (0.931, 1.130) |
AUC(0-∞)
| 0.997 | (0.879, 1.131) |
t1/2
| 0.939 | (0.711, 1.240) |
tmax, h | 0.00 (difference) | (-4.00, 3.00) |
-
AUC
0-168h
area under the concentration-time curve from time 0 to 168 h postdose, AUC
0-∞
area under the concentration-time curve from time 0 to infinity, AUC
0-t
area under the concentration-time curve from time 0 to the time of last observed concentration, CI confidence interval, C
max
maximum concentration; PK pharmacokinetic, t
max
time at which Cmax occurred, t
1/2
apparent half-life of terminal elimination
-
aAll PK parameters are corrected for predose FSH except for tmax