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Table 2 Development potential of oocytes and embryos after 4 weeks of CUMS

From: HSP70 overexpression may play a protective role in the mouse embryos stimulated by CUMS

 

Control group

Mild stress group

Moderate stress group

Severe stress group

P value

No. of mice

20

20

20

20

 

No. of oocytesa

32 ± 7

29 ± 5

22 ± 6*

15 ± 5*

<0.05

Fertilization rateb

87 %

78 %

61 %*

40 %*

<0.05

No. of 2-cell embryosa

27 ± 5

22 ± 4

15 ± 5*

9 ± 2*

<0.05

No. of D4 embryosa

24 ± 4

18 ± 3

10 ± 4*

4 ± 2*

<0.05

No. of high quality embryosa

20 ± 5

13 ± 4

5 ± 2*

1 ± 1*

<0.05

High quality embryo rateb

83 %

72 %

50 %*

25 %*

<0.05

No. of blastocystsa

8 ± 3

5 ± 2

2 ± 1*

1 ± 1*

<0.05

Blastocyst information rateb

33 %

28 %

20 %

25 %

NS

  1. aData are shown as the mean ± SD and were analyzed by ANOVA and LSD testing
  2. bData are shown as rates and were analyzed by χ 2 test and the partitioning χ 2 method
  3. *P < 0.05 compared with the control group, measured by LSD test or the partitioning χ 2 method. NS not significant