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Table 2 Comparison of true polycystic ovary syndrome (PCOS) on chart review in women with PCOS determined using ICD-9 codes or using an algorithm incorporating natural language processing and codified data

From: Identification of subjects with polycystic ovary syndrome using electronic health records

Method ICD-9 Code PCOS Algorithm-definite PCOS algorithm-probable P value*
Number of Charts 200 150 41  
Chart Reviewed Definite PCOS (%) 132 (66) 98 (65) 25 (61) 0.2*
Chart Reviewed Probable PCOS (%) 29 (14.5) 33 (22) 7 (17) 0.2
Not PCOS (%) 17 (8.5) 10 (7) 8 (20) 0.9
Unable to Determine (%) 22 (11) 9 (6) 1 (2) 0.04
  1. For the algorithm PCOS diagnoses, Definite or Probable were defined by probability cutoff levels. Chart reviewed definite PCOS had at least two confirmatory diagnostic criteria to support the diagnosis and probable had at least one confirmatory criterion
  2. *The p value for the algorithm was calculated using both the definite and probable categories