Table 1 Descriptive statistics of potential predictors (covariates) for ovarian response and their univariate correlation with high and low ovarian response
Covariate | Overall | Low (<6 oocytes) | Normal (6–18 oocytes) | High (>18 oocytes) | High versus normal/low | Low versus normal/high |
|---|---|---|---|---|---|---|
(n = 686) | (n = 159) | (n = 430) | (n = 97) | (P-value) | (P-value) | |
Age at baseline, y, mean (SD) | 38.0 (2.2) | 38.6 (2.2) | 37.9 (2.1) | 37.3 (2.1) | <0.001 | <0.001 |
Age at menarche, y, mean (SD) | 12.9 (1.5) | 12.6 (1.4) | 12.9 (1.5) | 13.1 (1.6) | 0.097 | 0.026 |
Average menstrual cycle length, days, mean (SD) | 28.2 (1.7) | 27.5 (1.5) | 28.3 (1.7) | 28.7 (1.7) | <0.001 | <0.001 |
Duration of infertility, y, mean (SD) | 2.8 (2.8) | 2.5 (2.3) | 2.9 (2.8) | 3.2 (3.2) | 0.169 | 0.100 |
BMI at baseline, kg/m2, mean (SD) | 25.1 (3.6) | 25.1 (3.6) | 25.1 (3.7) | 25.0 (3.4) | 0.705 | 0.893 |
AFC at day 1 of stimulation, n, mean (SD) | 10.8 (4.0) | 7.8 (3.1) | 11.2 (3.6) | 14.5 (3.4) | <0.001 | <0.001 |
(n = 679) | (n = 157) | (n = 426) | (n = 96) | |||
FSH at day 1 of stimulation, IU/L, median | 6.9 | 8.2 | 6.9 | 6.1 | <0.001 | <0.001 |
LH at day 1 of stimulation, IU/L, median | 4.6 | 4.2 | 4.7 | 4.7 | 0.555 | 0.089 |
Estradiol at day 1 of stimulation, pmol/L, median | 140.6 | 140.2 | 141.5 | 138.4 | 0.163 | 0.981 |
Progesterone at day 1 of stimulation, nmol/L, median | 1.9 | 1.9 | 1.9 | 2.0 | 0.984 | 0.849 |
AMH at day 1 of stimulation, ng/mL, median | 1.5 | 0.5 | 1.6 | 3.2 | <0.001 | <0.001 |