Comparison of two different methods for measuring anti-mullerian hormone in a clinical series

Table 1 Performance of Beckmann Coulter AMH Gen II ELISA and Elecsys Roche AMH assay

	ELISA (n = 38)		Cobas (n = 40)
	Level	CV%	Level	CV%
Control 1	40 pmol/l	5.2	40 pmol/l	3.3
Control 2	20 pmol/l	6.2	-	-
Control 3	7 pmol/l	10.3	7 pmol/l	2.8
Total CV% (<10 pmol/l) (n = 11)	31.9 (11.9–47.3)		28.0 (9.5–43.0
Total CV% (>10 pmol/l) (n = 12)	22.0 (11.9–35.2)		21.3 (11.6–33.6)
Percentage of samples without quantitation	15 %		2 %

Controls were analyzed on consecutive days of analysis over a period of 3 months. Data are given as CV% (Standard deviation x 100/ mean). Results of variance of clinical samples are given in two levels: < and >10 pmol/l (because of bias between the two methods, the level differ between the two groups.). Data are given as CV% (range). Percentage of samples without quantiation is determined as the percentage of results < 3 pmol/l (ELISA), and < 0.5 pmol/l (Elecsys Cobas)

ISSN: 1477-7827