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Table 6 Postpartum urinary steroid hormone concentrations

From: Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum

  6 weeks postpartum (n = 40)
Steroid μg per mmol creatinine    Reference intervals
move to a separate row Mean ± SD Median 2.5th percentile [90 % CI] 97.5th percentile [90 % CI]
Androsterone 130 ± 116 99.8 6.5 [6.2, 24.2] 524 [482, 525]
Etiocholanolone 180 ± 120 149 19.4 [19.3, 42.7] 456 [423, 457]
11-Oxo-Etiocholanolone 51.0 ± 35.1 42.1 8.0 [8.0, 14.9] 156 [149, 156]
11β-Hydroxy-Androsterone 77.5 ± 51.4 71.1 4.4 [4.2, 19.1] 262 [149, 156]
11β-Hydroxy-Etiocholanolone 46.4 ± 36.6 38.3 4.8 [4.8, 9.3] 161 [150, 161]
Dehydroepiandrosterone 33.5 ± 57.1 10.4 0.8 [0.8, 2.7] 291 [160, 294]
5-Androstene-3β,17β-diol 14.2 ± 15.1 9.4 0.4 [0.4, 1.6] 68.0 [50.0, 68.4]
5-Androstene-3β,17β-triol 9.8 ± 21.5 3.1 0.2 [0.2, 0.6] 113 [76.5, 114]
16α-Hydroxy-dehydroepiandrostrerone 46.8 ± 86.8 22.8 0.9 [0.9, 3.1] 502 [212, 510]
5-Androstene-3β,16α,17β-triol 40.4 ± 45.9 29.6 3.7 [3.6, 9.5] 271 [116, 275]
5-Pregnene-3β,16α,17,20α-triol 13.5 ± 12.5 10.7 0.4 [0.4, 1.3] 59.5 [38.9, 60.0]
Testosterone 3.7 ± 5.7 1.4 0.1 [0.1, 0.5] 26.0 [22.9, 26.1]
5α-Dihydrotestosterone 2.5 ± 2.3 2.2 0.1 [0.1, 0.6] 12.4 [8.2, 12.3]
Oestrogen metabolites
 Estriol 119 ± 339 17.6 0.9 [0.9, 1.4] 2011 [557, 2049]
 17β-Estradiol 2.9 ± 9.6 0.5 0.1 [0.05, 0.1] 58.7 [9.0, 60.0]
Progesterone precursor and metabolites
 Pregnenolone 9.8 ± 13.4 4.7 0.2 [0.2, 0.7] 52.5 [49.7, 52.2]
 17-Hydroxypregnanolone 20.2 ± 41.4 9.9 0.9 [0.9, 2.4] 257 [76.6, 262]
 Pregnanediol 257 ± 668 76.2 10.4 [10.3, 29.5] 4052 [1173, 4126]
 Pregnanetriol 56.0 ± 49.7 44.3 5.9 [5.7, 20.8] 297 [144, 301]
 11-Oxo-Pregnanetriol 2.8 ± 3.4 1.6 0.4 [0.4, 0.7] 17.7 [10.1, 17.8]
11-Deoxysteroid metabolites
 Tetrahydro-11-deoxycortisol 11.1 ± 8.6 9.8 0.7 [0.7, 3.0] 43.1 [30.6, 42.8]
 Tetrahydro-11-deoxycorticosterone 28.2 ± 160 1.3 0.1 [0.1, 0.4] 989 [27.0, 1014]
Corticosterone metabolites
 Tetrahydroaldosterone 4.2 ± 4.6 2.6 0.5 [0.5, 1.1] 21.9 [19.3, 21.9]
 Tetrahydro-11-dehydrocorticosterone 20.7 ± 23.5 14.6 0.4 [0.4, 3.3] 139 [53.9, 142]
 Tetrahydrocorticosterone 23.8 ± 16.7 20.1 2.2 [2.2, 6.8] 71.3 [69.3, 71.3]
 5a-Tetrahydrocorticosterone 35.7 ± 28.1 28.8 1.7 [1.6, 6.3] 143 [113, 143]
Cortisone metabolite
 Cortisone 28.2 ± 20.1 23.4 1.0 [1.0, 10.3] 101 [74.8, 101]
 Tetrahydrocortisone 397 ± 233 373 58.8 [58.2, 120] 1034 [906, 1037]
 α-Cortolon 122 ± 117 90.5 18.1 [18, 33.5] 707 [286, 718]
 β-Cortolon 30.6 ± 40.4 6.1 0.2 [0.2, 1.5] 156 [141, 155]
 20α-Dihydrocortisone 3.4 ± 2.7 2.7 0.2 [0.2, 1.1] 13.5 [9.7, 13.6]
 20β-Dihydrocortisone 9.2 ± 6.9 8.1 0.5 [0.4. 3.1] 34.3 [24.5, 34.5]
Cortisol metabolites
 Cortisol 20.8 ± 19.1 13.8 0.9 [0.8, 4.1] 99.7 [66.7, 99.7]
 Tetrahydrocortisol 256 ± 153 243 30.7 [30.3, 80.3] 723 [599, 726]
 5α-Tetrahydrocortisol 97.1 ± 81.2 78.3 5.8 [5.4, 22.7] 381 [302, 383]
 α-Cortol 41.1 ± 32.6 35.5 3.9 [3.8, 17.7] 203 [98.2, 206]
 β-Cortol 55.3 ± 29.2 50.1 10.0 [9.9, 25.8] 130 [114, 130]
 20α-Dihydrocortisol 17.3 ± 22.6 9.3 0.2 [0.2, 3] 127 [50.7, 127]
 6β-Hydroxycortisol 149 ± 25.8 26.5 0.9 [0.9, 8.1] 149 [77.9, 149]
 18-Hydroxycortisol 322 ± 55.1 41.7 1.5 [1.4, 4.9] 322 [130, 322]