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Table 4 Steroid hormone metabolite[μg/mmol urinary creatinine]

From: Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum

  1st trimester (n = 81) 2nd trimester (n = 40) 3rd trimester (n = 40)
   Reference intervals    Reference intervals    Reference intervals
move to a separate row Mean ± SD Median 2.5th percentile [90 % CI] 97.5th percentile [90 % CI] Mean ± SD Median 2.5th percentile [90 % CI] 97.5th percentile [90 % CI] Mean ± SD Median 2.5th percentile [90 % CI] 97.5th percentile [90 % CI]
Tetrahydro-11-deoxycortisol 17.1 ± 10.1 15.5 2.7 [1.2, 6.9] 43.1 [35.1, 62.5] 23.2 ± 11.5 21.2 5.2 [5.1, 11.3] 56.2 [51.9, 56.3] 37.1 ± 27.4 31.6 8.9 [8.9, 11.4] 146 [110, 147]
Tetrahydro-11-deoxycorticosterone 12.5 ± 8.8 10.2 1.7 [0.9, 3.8] 40.1 [33.9, 46.6] 35.3 ± 102 16.1 4.1 [4.1, 5.9] 643 [466, 629] 588 ± 1681 31.6 6.1 [6.1, 14.7] 8789 [5075, 8875]
Corticosterone metabolites
 Tetrahydroaldosterone 15.4 ± 10.7 12.0 2.7 [2.1, 5.0] 49.8 [36.5, 65.6] 18.2 ± 19.5 11.4 1.6 [1.6, 3.9] 114 [40.6, 116] 22.9 ± 16.6 18.2 2.1 [2.1, 7.1] 87.1 [55.1, 87.9]
 Tetrahydro-11-dehydrocorticosterone 33.6 ± 23.7 26.7 3.9 [3.2, 10.9] 108 [88.5, 130] 35.1 ± 19.3 30.3 10.2 [10.1, 15.8] 89.4 [87.1, 89.4] 88.0 ± 88.9 56.1 13.4 [13.3, 27.4] 385 [371, 386]
 Tetrahydrocorticosterone 23.1 ± 12.7 21.4 3.4 [3.0, 8.1] 57.8 [48.5, 63.4] 25.8 ± 13.2 22.3 3.3 [3.2, 8.5] 57.9 [55.0, 58.0] 83.0 ± 107.3 43.4 15.2 [15.1, 22.5] 586 [344, 591]
 5α-Tetrahydro-corticosterone 51.5 ± 39.3 39.8 5.9 [4.3, 13.9] 189 [143, 194] 33.8 ± 21.6 30.0 1.7 [1.6, 9.8] 93.0 [91.7, 93] 59.0 ± 62.4 33.8 5.6 [5.6, 15.0] 304 [241, 306]