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Table 3 Steroid hormone metabolite[μg/mmol urinary creatinine]

From: Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum

  1st trimester (n = 81) 2nd trimester (n = 40) 3rd trimester (n = 40)
   Reference intervals    Reference intervals    Reference intervals
move to a separate row Mean ± SD Median 2.5th percentile [90 % CI] 97.5th percentile [90 % CI] Mean ± SD Median 2.5th percentile [90 % CI] 97.5th percentile [90 % CI] Mean ± SD Median 2.5th percentile [90 % CI] 97.5th percentile [90 % CI]
Estriol 135 ± 151 79.9 10.6 [3.5, 17.0] 545 [489, 901] 975 ± 584 836 143 [143, 2881] 2877 [2660, 2881] 2651 ± 2651 1955 636 [636, 764] 15192 [9171, 15116]
17β-Estradiol 9.1 ± 6.7 7.3 0.7 [0.6, 2.1] 26.4 [24.8, 28.8] 16.6 ± 12.0 14.5 1.8 [1.8, 4.6] 63.5 [45.0, 64.0] 25.2 ± 25.2 24.0 2.3 [2.3, 8.9] 117 [111, 117]
Progesterone metabolites
 Pregnenolone 14.2 ± 10.0 12.5 2.8 [2.6, 4.2] 53.0 [41.3, 54] 18.0 ± 14.7 14.9 1.9 [1.9, 3.3] 65.3 [57.3, 65.5] 27.9 ± 42.4 16.9 4.2 [4.2, 6.2] 265 [94.2, 265]
 17-Hydroxypregnanolone 91.0 ± 76.4 79.5 14.6 [9.1, 23.1] 229 [202, 599] 88.3 ± 55.5 72.8 18.8 [18.7, 41.9] 247 [238, 247] 189 ± 253 113 34.1 [34.2, 50.6] 1298 1051, 1298]
 Pregnanediol 1269 ± 830 1110 215 [154, 416] 4257 [3093, 4405] 1765 ± 1291 1461 459 [457, 633] 7514 [4181, 7602] 3982 ± 3762 2877 785 [779, 1162] 21112 [11216, 21112]
 Pregnanetriol 209 ± 114 191 53.9 [34.2, 80.9] 455 [378, 774] 182 ± 94.0 153 35.8 [34.6, 99.6] 480 [443, 481] 287 ± 321 191 53.9 [53.4, 89.2] 1865 [970, 1865]
 11-Oxopregnanetriol 2.7 ± 2.7 2.0 0.4 [0.3, 0.7] 11.8 [10.5, 14.7] 2.8 ± 4.4 1.5 0.3 [0.3, 0.7] 26.4 [10.0, 26.9] 11.3 ± 29.2 1.9 0.2 [0.2, 0.5] 151 [99.2, 1501]