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Table 2 MMP and TIMP activities in the follicular fluid between high and low oocyte maturity groups

From: Matrix metalloproteinase 2 level in human follicular fluid is a reliable marker of human oocyte maturation in in vitro fertilization and intracytoplasmic sperm injection cycles

Ā 

High oocyte maturity group (MII oocytesā€‰=ā€‰100Ā %)

Low oocyte maturity group (MII oocytesā€‰<ā€‰100Ā %)

P value

Number of patients

95

55

Ā 

Estradiol (pg/ml)

2774ā€‰Ā±ā€‰1078

2651ā€‰Ā±ā€‰1829

NS

Progesterone (ng/ml)

0.81ā€‰Ā±ā€‰0.78

0.69ā€‰Ā±ā€‰0.39

NS

MII oocytes ratio (%)

100ā€‰Ā±ā€‰0

76.4ā€‰Ā±ā€‰15.8

< 0.001

2PN embryos ratio (%)

75.9ā€‰Ā±ā€‰24.4

68.8ā€‰Ā±ā€‰23.8

NS

D5 GB embryos ratio (%)

45.8ā€‰Ā±ā€‰32.5

29.8ā€‰Ā±ā€‰33.5

< 0.01

MMP-2 (Arbitrary units/Ī¼l)

19.6ā€‰Ā±ā€‰4.3

16.3ā€‰Ā±ā€‰4.3

< 0.001

MMP-9 (Arbitrary units/Ī¼l)

2.11ā€‰Ā±ā€‰0.59

2.19ā€‰Ā±ā€‰0.74

NS

TIMP-1 (ng/ml)

123ā€‰Ā±ā€‰37

107ā€‰Ā±ā€‰26

NS

TIMP-2 (ng/ml)

54.6ā€‰Ā±ā€‰16.5

52.6ā€‰Ā±ā€‰13.6

NS

  1. MII Metaphase II, 2PN Two pronuclei, D5 GB Good-quality blastocysts on day 5, MMP Matrix metalloproteinase, TIMP Tissue inhibitor of matrix metalloproteinase
  2. Values are expressed as the meanā€‰Ā±ā€‰SD. P values are comparisons between the high- and low-maturity groups by ANOVA.; NS: no statistical significance (i.e., Pā€‰>ā€‰0.05)