Skip to main content

Table 2 Biological and clinical outcomes of two study arms

From: RETRACTED ARTICLE: Intracytoplasmic morphologically selected sperm injection versus conventional intracytoplasmic sperm injection: a randomized controlled trial

  IMSI (n. 48) cICSI (n. 73) P
Sperm count (million/ml) 22.6 ± 24.6 22.9 ± 23.7 0.947
Motility (% total count) 29.6 ± 16.0 24.5 ± 12.8 0.055
Morphologically normal spermatozoa (% total count) 2.9 ± 2.2 2.8 ± 2.3 0.812
Sperm morphology by MSOME criteria (n., %)
Normal nuclei 160/219; 73.0 --- ---
First choice selected sperm 33/219; 15.1 --- ---
Second choice selected sperm 21/219; 9.6 --- ---
Third choice selected sperm 5/219; 2.3 --- ---
Aspirated cycles (n.) 48 73 ---
Retrieved oocytes (n.) 6.3 ± 2.7 6 ± 3.5 0.6157
MII oocytes retrieved (n.) 5.1 ± 2.5 5.3 ± 3.1 0.709
Oocytes inseminated (n.) 4.6 ± 1.9 4.6 ± 2.8 1.000
Fertilization rate (n.; %) 105/219; 47.9 211/333; 63.4 0.001
Embryo obtained (n.) 99, 2.1 ± 1.7 221, 3.0 ± 1.9 0.009
Good quality embryos rate (n.; %) 73/99; 73.7 167/221; 75.6 0.834
ET rate (n.; %) 34/48; 70.8 64/73; 87.7 0.038
Embryo transferred (n.) 65, 1.4 ± 1.0 137, 1.9 ± 1.2 0.018
Implantation rate (n.; %) 15/65; 23.1 18/137; 13.1 0.102
Total pregnancies (n.) 14 19 ---
Total pregnancy rate//initiated cycles (n.; %)a 14/48; 29.2 19/73; 26.0 0.865
Total pregnancy rate/ET (n.; %) 14/34; 41.2 19/64; 29.7 0.952
OHSS rate (n.; %) 5/48; 10.4 6/73; 8.2 0.930
Biochemical pregnancy rate (n., %) 3/14; 21.4 4/19; 21.1 0.859
Clinical pregnancies (n.) 11 15 ---
Clinical pregnancy rate/initiated cycles (n.; %)* 11/48; 22.9 15/73; 20.5 0.823
Clinical pregnancy rate/ET rate (n.; %) 11/34; 32.3 15/64; 23.4 0.349
Miscarriage rate (n.; %) 2/11; 18.2 4/15; 26.7 1.000
Multiple pregnancies rate (n.; %) 4/11; 36.4 4/15; 26.7 0.683
Delivery live births (n.) 9 11 ---
Delivery live birth rate/initiated cycles (n.; %)* 9/48; 18.8 11/73; 15.1 0.624
Delivery live birth rate/ET (n.; %) 9/34; 26.5 11/64; 17.2 0.301
Twin deliveries 2/9; 22.2 4/11; 36.4 0.496
Live births 11 14  
Cycles with embryo freezing 9/48; 18.8 13/73; 17.8 0.895
Embryo thawing cycles 9 7 ----
Embryo thawing ET 6/9; 66.7 5/7; 71.4 0.839
Embryo thawing clinical pregnancies 0/6; 0 2/5; 40 0.186
Embryo thawing deliveries 0/6 1/5; 20 0.528
Total delivery live birth rate/initiated cycle (n., %) 9/48; 18.8 12/73; 16.4 0.743
  1. Data expressed as mean ± SD or as number/percentage. MII metaphase II, MOSOME motile sperm organelle morphology examination, PU pick-up, ET embryo transfer, OHSS ovarian hyperstimulation syndrome, aBecause no cycle was cancelled, the initialled cycles corresponded to the aspirated cycles