Skip to main content

Table 4 Most highly up- and down-regulated DEGs within epithelial cells of the isthmus in follicular phase versus luteal phase groups (FDR adjusted P < 0.05)

From: A transcriptomal analysis of bovine oviductal epithelial cells collected during the follicular phase versus the luteal phase of the estrous cycle

Gene Symbol Gene Description P-value Fold-Change
 KRT23 keratin 23 (histone deacetylase inducible) <0.001 22.57
 NTS neurotensin <0.001 21.57
 PRND prion protein 2 (dublet) <0.001 12.36
 STRA6 stimulated by retinoic acid gene 6 homolog (mouse) <0.001 11.22
 TMEM45A transmembrane protein 45A 0.004 10.56
 PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 0.004 9.86
 LPL lipoprotein lipase <0.001 9.40
 SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 <0.001 8.92
 CLEC3A C-type lectin domain family 3, member A <0.001 8.69
 GFAP glial fibrillary acidic protein <0.001 8.09
 CRELD2 cysteine-rich with EGF-like domains 2 <0.001 7.69
 CA2 carbonic anhydrase II <0.001 7.68
 PLA2G4D phospholipase A2, group IVD (cytosolic) <0.001 7.64
 CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.001 7.34
 SDF2L1 stromal cell-derived factor 2-like 1 <0.001 7.31
 PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.000 7.30
 P2RX2 purinergic receptor P2X, ligand-gated ion channel, 2 0.002 6.86
 PLA2G4F phospholipase A2, group IVF <0.001 6.85
 SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 <0.001 6.69
 CDC20B cell division cycle 20 homolog B (S. cerevisiae) 0.001 6.35
Gene Symbol Gene Description P-value Fold-Change
 KLF17 Kruppel-like factor 17 <0.001 −14.70
 KSR2 kinase suppressor of ras 2 <0.001 −8.94
 LOC100337391 predicted protein-like <0.001 −7.77
 BSP3 binder of sperm 3 <0.001 −7.58
 OR9Q2 olfactory receptor, family 9, subfamily Q, member 2 0.001 −6.87
 ZBTB16 zinc finger and BTB domain containing 16 <0.001 −5.91
 EGR1 early growth response 1 0.019 −5.35
 LOC522479 ovalbumin-like <0.001 −5.34
 CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 0.001 −5.09
 TFF3 trefoil factor 3 (intestinal) <0.001 −4.98
 LOC100335668 mitochondrial import inner membrane translocase subunit Tim9 pseudogene 0.001 −4.94
 LOC617981 family with sequence similarity 55, member C-like <0.001 −4.92
 MEGF10 multiple EGF-like-domains 10 <0.001 −4.81
 LOC100337183 contactin associated protein-like 3-like 0.003 −4.75
 AK5 adenylate kinase 5 <0.001 −4.74
 FOS FBJ murine osteosarcoma viral oncogene homolog 0.012 −4.54
 CA10 carbonic anhydrase X 0.001 −4.40
 NDP Norrie disease (pseudoglioma) <0.001 −4.34
 SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1- like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A <0.001 −4.26
 CAV1 caveolin 1, caveolae protein, 22 kDa 0.003 −4.14
  1. For statistical analysis, an F-test on least-square means was used to determine significance of each transcript in each comparison. Benjamini-hochberg multiple testing correction for false discovery rate (FDR) was applied and significance set to FDR adjusted P-value < 0.05. A post-hoc pairwise comparison of FP compared to LP epithelial cells from the isthmus was completed using Fisher’s Least Significant Difference (LSD) to determine which means differed
Back to article page

Reproductive Biology and Endocrinology

ISSN: 1477-7827

Contact us