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Table 3 Most highly up- and down-regulated DEGs within epithelial cells of the ampulla in follicular versus luteal phase groups (FDR adjusted P < 0.05)

From: A transcriptomal analysis of bovine oviductal epithelial cells collected during the follicular phase versus the luteal phase of the estrous cycle

Gene Symbol

Gene description

P-value

Fold-Change

 NTS

Neurotensin

<0.001

32.44

 PRND

prion protein 2 (dublet)

<0.001

18.30

 CDC20B

cell division cycle 20 homolog B (S. cerevisiae)

<0.001

17.49

 bTrappin-5

trappin 5

<0.001

11.14

 TMEM45A

transmembrane protein 45A

0.004

10.69

 CRELD2

cysteine-rich with EGF-like domains 2

<0.001

9.98

 SLC2A10

solute carrier family 2 (facilitated glucose transporter), member 10

<0.001

9.54

 SDF2L1

stromal cell-derived factor 2-like 1

<0.001

9.29

 MIR449C

microRNA mir-449c

<0.001

9.20

 KRT23

keratin 23 (histone deacetylase inducible)

0.004

8.40

 DNAJB11

DnaJ (Hsp40) homolog, subfamily B, member 11

<0.001

6.92

 MANF

mesencephalic astrocyte-derived neurotrophic factor

<0.001

6.90

 MFSD2A

major facilitator superfamily domain containing 2A

<0.001

6.70

 CLPH

calcium-binding protein, spermatid-specific 1 (CABS1)

<0.001

6.61

 PLA2G4D

phospholipase A2, group IVD (cytosolic)

<0.001

6.61

 CBLN4

cerebellin 4 precursor

<0.001

6.57

 SERPINE3

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3

<0.001

6.54

 RRM2

ribonucleotide reductase M2

<0.001

6.52

 H4

histone H4

<0.001

6.30

 INSIG1

insulin induced gene 1

<0.001

6.21

Gene Symbol

Gene Description

P-value

Fold-Change

 EGR1

early growth response 1

0.005

−9.13

 FOS

FBJ murine osteosarcoma viral oncogene homolog

0.002

−8.55

 VCAM1

vascular cell adhesion molecule 1

<0.001

−7.11

 GABRP

gamma-aminobutyric acid (GABA) A receptor, pi

<0.001

−6.76

 GPR174

G protein-coupled receptor 174

0.003

−5.15

 ZBTB16

zinc finger and BTB domain containing 16

0.001

−4.62

 BMP4

bone morphogenetic protein 4

0.001

−4.44

 LOC777601

uncharacterized LOC777601

<0.001

−4.37

 FIGF

c-fos induced growth factor (vascular endothelial growth factor D)

<0.001

−4.12

 KLRK1

killer cell lectin-like receptor subfamily K, member 1

0.003

−4.09

 PDK4

pyruvate dehydrogenase kinase, isozyme 4

0.001

−3.93

 LOC100297676

C-type lectin domain family 2 member G-like

0.003

−3.78

 LOC100337183

contactin associated protein-like 3-like

0.008

−3.71

 LOC768255

GTPase, IMAP family member 4-like

0.001

−3.64

 TRAT1

T cell receptor associated transmembrane adaptor 1

0.007

−3.48

 CAPN6

calpain 6

0.007

−3.48

 CAV1

caveolin 1, caveolae protein, 22 kDa

0.005

−3.44

 LOC541007

Similar to protein jade-2(PHD finger protein 15) (BT24231-RA)

<0.001

−3.34

 CHRDL1

chordin-like 1

0.002

−3.31

 MIR29C

microRNA mir-29c

0.001

−3.29

  1. For statistical analysis, an F-test on least-square means was used to determine significance of each transcript in each comparison. Benjamini-hochberg multiple testing correction for false discovery rate 2 (FDR) was applied and significance set to FDR adjusted P-value < 0.05. A post-hoc pairwise comparison of FP compared to LP epithelial cells from the ampulla was completed using Fisher’s Least Significant Difference (LSD) to determine which means differed