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Table 5 Comparisons of demographic and clinical characteristics between subgroups of the day 3 ET group

From: Progesterone elevation on the day of human chorionic gonadotropin administration adversely affects the outcome of IVF with transferred embryos at different developmental stages

Parametera Serum P levels (ng/ml), day 3 ETb
  <1.0 1.0-1.49 ≥1.5
No. of fresh cycles 7627 2373 846
Female age (years) 31.1 ± 5.1 31.8 ± 5.0* 32.1 ± 5.1
BMI (kg/m2) 22.7 ± 3.2 22.3 ± 3.0* 22.1 ± 3.0
Basal FSH (IU/L) 7.7 ± 2.9 7.3 ± 2.4* 7.2 ± 2.2
Total dose of Gn (IU) 2201.2 ± 940.7 2268.6 ± 879.3* 2357.1 ± 890.1*
Serum E2 (pg/ml), hCG day 3941.8 ± 2118.6 5321.0 ± 2353.8* 6201.8 ± 4598.0*
Serum LH (IU/L), hCG day 2.0 ± 1.3 1.9 ± 1.4 1.72 ± 1.9*
Endometrial thickness (mm), hCG day 12.3 ± 2.4 12.2 ± 2.5 12.0 ± 2.4*
No. of oocytes retrieved 9.3 ± 4.4 11.1 ± 4.6* 12.0 ± 4.8*
No. of 2PN oocytes 6.4 ± 3.3 7.5 ± 3.5* 7.8 ± 4.8
No. of 2PN cleavage embryos 6.4 ± 3.3 7.5 ± 3.5* 7.8 ± 4.8
No. of available embryos 5.0 ± 2.8 5.7 ± 3.0* 5.9 ± 3.2
Fertilization rate (%) 69 67.4* 65.1*
Cleavage rate (%) 97.8 97.7 97.3**
No. of transferred embryos 2.10 ± 0.34 2.12 ± 0.34* 2.14 ± 0.39
No. of transferred top-quality embryos 1.97 ± 0.55 2.00 ± 0.53** 2.02 ± 0.56*
Implantation rate (%) 36.3 31.6* 26*
CPR (%) 50.4 45.5* 36.2*
  1. Note: Day 3 ET subgroups according progesterone cut-off levels: <1 ng/ml, 1–1.49 ng/ml, and ≥1.5 ng/ml. P = progesterone
  2. aAll values are presented as the mean ± SD or count (%)
  3. bDifferences between subgroups were determined using ANOVA followed by the LSD-t test or the Kruskal-Wallis (KW) test and subsequent pairwise multiple comparisons for continuous variables and the chi-square test or Fisher’s exact test for categorical variables
  4. *p < 0.01 compared with the previous subgroup
  5. **p < 0.05 compared with the previous subgroup