Table 2 Reported cases of testis-related tumours in aneuploidies
From: Leydig cell tumor in a patient with 49,XXXXY karyotype: a review of literature
References | No. of Patients | Karyotype | Tumour type |
|---|---|---|---|
Yoshida [89] | One | 47,XXY | Germ cell tumour |
Carroll [90] | One | 47,XXY | Germ cell tumour |
Sasagawa [91] | Two | 47,XXY | Germ cell tumours |
Baniel [92] | One | 47,XXY | Benign epidermal cyst |
Reddy [93] | One | 48,XXYY | Seminoma |
Isurugi [94] | One | 47,XXY | Seminoma |
Tada [95] | One | 47,XXY | Teratoma |
Stevens [96] | One | 47,XXY | Bilateral teratoma |
Matsuki [97] | One | 46,XX/47,XXY | Mature Teratoma |
Simpson [98] | Two brothers | 47,XXY | Teratomas |
Gustavson [99] | Two | 47,XXY | Bilateral Teratomas |
Ekerhovd [100] | One | 47,XXY | Sertoli cell tumour |
Lardennois [101] | One | 47,XXY | Bilateral Leydig cell tumours |
Soria [102] | One | 47,XXY | Malignant Leydig cell tumour |
Arduino [103] | One | 47,XXY | Benign Leydig cell tumour |
Dodge [104] | One | 47,XXY | Benign Leydig cell tumour |
Knyrim [105] | One | 47,XXY | Malignant Leydig cell tumour |
Poster [106] | One | 47,XXY | Benign Leydig cell tumour |
Okada [107] | One | 47,XXY | Benign Leydig cell tumour |
Westlander [108] | One | 47,XXY | Leydig cell tumour |
Heer [109] | One | 47,XXY | Leydig cell tumour |
Fishman [110] | One | 47,XXY | Benign Leydig cell tumour |
Miazlin [77] | One | 47,XXY | Benign Leydig cell tumour |
De Miguel [111] | Five | 47,XXY | Leydig cell hyperplasia in all |