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Table 3 Association of 25(OH)D with sex-related hormones

From: Vitamin D is associated with testosterone and hypogonadism in Chinese men: Results from a cross-sectional SPECT-China study

 

25(OH)D, nmol/L

Dependent variables

Model 1

Model 2

Model 3

Total T, nmol/L

0.056 (0.038, 0.074)***

0.031 (0.011, 0.051)**

0.023 (0.004, 0.042)*

Log (free T), pmol/L

−0.002 (−0.003, −0.001)***

−0.001 (−0.001, 0.000)

−0.001 (−0.001, 0.000)

E2, pmol/L

0.866 (0.671, 1.061)***

0.264 (0.054, 0.475)*

0.238 (0.023, 0.452)*

Log SHBG, nmol/L

0.004 (0.004, 0.005)***

0.001 (0.000, 0.002)**

0.001 (0.000, 0.001)

Log LH, IU/L

0.004 (0.003, 0.004)***

0.001 (0.000, 0.001)*

0.001 (0.000, 0.001)

Log FSH, IU/L

0.005 (0.004, 0.006)***

0.001 (0.000, 0.002)*

0.001 (0.000, 0.002)

  1. The data are expressed as B coefficient (95 % confidence interval)
  2. T, testosterone; E2, estradiol; SHBG, sex hormone binding globulin
  3. Model 1 was unadjusted. Model 2 included terms for age, residence area, economic status and current smoker. Model 3 included terms for model 2, BMI, log (HOMA-IR), diabetes and systolic pressure. To obtain the average percentage change in free T, SHBG, LH or FSH from log hormone = 100 × (exp(B coefficient) - 1)
  4. *P < 0.05, **P < 0.01, ***P < 0.001. Linear regression analysis was used