Table 2 Embryological and clinical outcomes
From: Ovarian hyperstimulation syndrome: a clinical report on 4894 consecutive ART treatment cycles
Parameters | HCG | Buserelin | OHSS | p |
|---|---|---|---|---|
Cycles | 4772 | 71 | 51 | |
COC | 36768 | 1134 | 563 | |
COC (mean) | 7.8 ± 4.7 | 16.0 ± 6.9 | 11.0 ± 4.0 | a,b,c |
MII | 30872 | 910 | 469 | |
Maturation rate (MII/COC) | 84.0 | 80.2 | 83.3 | a |
2PN/2 PB | 21410 | 648 | 346 | |
Fertilization rate (2PN/MII) | 69.4 | 71.2 | 73.8 | b |
Embryos cleaved | 20954 | 641 | 337 | |
Embryo cleavage rate (d2/2PN) | 97.9 | 98.9 | 97.4 | NS |
Embryo transfer cycles (ETC.) | 4391 | 67 | 51 | |
n° Embryos transferred (mean) | 8443-1.9 ± 0.5 | 121-1.8 ± 0.4 | 92-1.8 ± 0.4 | NS |
Biochemical pregnancy (/ETC.) | 1973-44.9 | 32-47.8 | 49-96.1 | b,c |
Clinical pregnancy (CP) (/ETC.) | 1709-38.9 | 20-29.9 | 48-94.1 | b,c |
Sacs | 2155 | 23 | 64 | |
Implantation rate (sacs/n°ET) | 25.5 | 19.0 | 69.6 | b,c |
Singletons (/CP) | 1197-70.0 | 9-45.0 | 29-60.4 | a |
Twins (/CP) | 473-27.7 | 7-35.0 | 16-33.3 | NS |
Triplets (/CP) | 11-0.6 | 0 | 1-2.1 | NS |
Ectopic pregnancy (/CP) | 28-1.6 | 4-20.0 | 2-4.2 | a,c |
Abortion (/CP) | 253-14.8 | 2-10.0 | 6-12.5 | NS |
Ongoing pregnancy (/ETC.) | 1428-32.5 | 14-20.9 | 40-78.4 | a,b,c |
Delivery (/ETC.) | 1329-30.3 | 14-20.9 | 40-78.4 | b,c |
Stillbirths (/ETC.) | 1-0.02 | 0 | 0 | NS |
Live-birth delivery rate (/ETC.) | 1328-30.2 | 14-20.9 | 40-78.4 | b,c |
Newborn (NB) (/ETC.) | 1655-37.7 | 19-28.4 | 53-100 | b,c |
Male (/NB) | 832-50.5 | 11-57.9 | 25-47.2 | NS |
Female (/NB) | 817-49.5 | 8-42.1 | 28-52.8 | NS |
Male/Female ratio | 1.0 | 1.4 | 0.90 | NS |
Newborn malformations (/NB) | 36-2.2 | 2-10.5 | 0 | a,c |
Major (/NB) | 27-1.6 | 2-10.5 | 0 | a,c |
Minor (/NB) | 9-0.5 | 0 | 0 | NS |
NB Chromosome abnormalities (/NB) | 5-0.3 | 0 | 0 | NS |
Early neonatal death (/ETC.) | 4-0.1 | 0 | 0 | NS |