Table 1 Experimental design

1

In vitro: effect of different amounts of PC on embryo development

705 oocytes

• Rate of embryos

• Total cell numbers per blastocyst

2

In vivo: evaluation of endometrial cell proliferation, after in vivo PC administration

4 RBCs

Microscopic nuclear count of cells expressing Ki-67

3

In vivo: embryo implantation and development after intrauterine administration of PC

30 Treated RBCs

30 Control RBCs

Rate of pregnancy