In the pubertal rat, the regulation of ovarian function involves the synergic participation of the sensory and sympathetic innervations that arrive at the gonad

Table 2 Ovulation rate by ovary (%)

Pharmacological procedure in new born and surgical procedure in 20-day-old rats
	Vehicle	Capsaicin	Vehicle	Capsaicin	Vehicle	Capsaicin	Vehicle	Capsaicin
	SO	SO	SSON-L	SSON-L	SSON-R	SSON-R	SSON-B	SSON-B
LEFT OVARY	89	100	21^ab	55	67	71	60	75
RIGHT OVARY	100	100	93	91	33^ac	71	70	75
Pharmacological procedure in new born and surgical procedure in 28-day-old rats
	Vehicle	Capsaicin	Vehicle	Capsaicin	Vehicle	Capsaicin	Vehicle	Capsaicin
	SO	SO	SSON-L	SSON-L	SSON-R	SSON-R	SSON-B	SSON-B
LEFT OVARY	73	100	50^ab	89	100	89	75	83
RIGHT OVARY	91	100	100	100	70	56	75	100

Percent of ovulation rate in animals treated with vehicle or capsaicin at birth and subjected to SON sectioning. Animals were treated with vehicle or capsaicin at birth. At 20 or 28 days of age, the animals were subjected to a sham-operation (SO) or were subjected to left (L), right (R) or bilateral (B) SSON. All animals were sacrificed at the first vaginal estrus. Significance was noted as indicated. ^a p <0.05 VEHICLE + SSON-L or VEHICLE + SSON-R vs. the contralateral ovary of the same group, Chi square test. ^b p <0.05 VEHICLE + SSON-L (left ovary) vs. VEHICLE + SO (left ovary), Chi square test. ^c p <0.05 VEHICLE + SSON-R (right ovary) vs. VEHICLE + SO (right ovary), Chi square test

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