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Table 3 The haplotype distributions of PTEN polymorphisms in POI patients and controls

From: No association between polymorphisms in PTEN and primary ovarian insufficiency in a Han Chinese population

Haplotype Total frequency Cases frequency Controls frequency p-value p-value from permutation
T-C-C-G-C 0.358 0.378 0.345 0.355 0.820
T-T-C-A-T 0.302 0.301 0.302 0.959 1.000
T-T-A-A-T 0.181 0.145 0.204 0.042 0.175
C-C-C-A-T 0.084 0.084 0.084 0.971 1.000
  1. The haplotype association analysis was performed using the HaploView 4.2 software. The p-value of T-T-A-A-T showed a statistically significant difference, but there was no significant difference after 104 permutation tests