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Table 2 The genotype frequencies of the seven SNPs in PTEN between POI patients and controls

From: No association between polymorphisms in PTEN and primary ovarian insufficiency in a Han Chinese population

SNP

Genotypes, n

Value

p

OR (95 % CI)

rs1234219

T/T

T/C

C/C

Missing

   

Cases

124

23

1

0

0.201

0.950

0.770 (0.069–8.584)

Controls

191

34

2

3

  

1.042 (0.586–1.852)

rs1903858

C/C

C/T

T/T

Missing

   

Cases

47

70

31

0

2.889

0.236

1.367 (0.837–2.233)

Controls

55

112

59

4

  

0.841 (0.496–1.425)

rs2299939

C/C

C/A

A/A

Missing

   

Cases

106

39

2

1

5.319

0.070

4.719 (1.043–21.353)

Controls

146

67

13

4

  

3.784 (0.811–17.651)

rs35352882

T/T

T/C

C/C

Missing

   

Cases

135

13

0

0

0.016

0.899

1.049 (0.502–2.195)

Controls

207

19

0

4

   

rs17107001

G/G

G/T

T/T

Missing

   

Cases

137

11

0

0

0.220

0.639

0.822 (0.363–1.864)

Controls

212

14

0

4

   

rs2299941

A/A

A/G

G/G

Missing

   

Cases

56

72

20

0

0.854

0.652

1.080 (0.568–2.052)

Controls

96

100

30

4

  

0.875 (0.455–1.684)

rs12572106

T/T/

T/C

C/C

Missing

   

Cases

47

71

30

0

2.048

0.359

1.501 (0.825–2.730)

Controls

87

102

37

4

  

1.288 (0.808–2.054)

  1. The genotype frequencies were performed with Pearson’s chi-squared test or Fisher’s exact test using SPSS 13.0 software. There was no significant difference between POI patients and the controls