Skip to main content

Table 2 The genotype frequencies of the seven SNPs in PTEN between POI patients and controls

From: No association between polymorphisms in PTEN and primary ovarian insufficiency in a Han Chinese population

SNP Genotypes, n Value p OR (95 % CI)
rs1234219 T/T T/C C/C Missing    
Cases 124 23 1 0 0.201 0.950 0.770 (0.069–8.584)
Controls 191 34 2 3    1.042 (0.586–1.852)
rs1903858 C/C C/T T/T Missing    
Cases 47 70 31 0 2.889 0.236 1.367 (0.837–2.233)
Controls 55 112 59 4    0.841 (0.496–1.425)
rs2299939 C/C C/A A/A Missing    
Cases 106 39 2 1 5.319 0.070 4.719 (1.043–21.353)
Controls 146 67 13 4    3.784 (0.811–17.651)
rs35352882 T/T T/C C/C Missing    
Cases 135 13 0 0 0.016 0.899 1.049 (0.502–2.195)
Controls 207 19 0 4    
rs17107001 G/G G/T T/T Missing    
Cases 137 11 0 0 0.220 0.639 0.822 (0.363–1.864)
Controls 212 14 0 4    
rs2299941 A/A A/G G/G Missing    
Cases 56 72 20 0 0.854 0.652 1.080 (0.568–2.052)
Controls 96 100 30 4    0.875 (0.455–1.684)
rs12572106 T/T/ T/C C/C Missing    
Cases 47 71 30 0 2.048 0.359 1.501 (0.825–2.730)
Controls 87 102 37 4    1.288 (0.808–2.054)
  1. The genotype frequencies were performed with Pearson’s chi-squared test or Fisher’s exact test using SPSS 13.0 software. There was no significant difference between POI patients and the controls