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Table 1 The allele frequencies of the seven SNPs in PTEN between POI patients and controls

From: No association between polymorphisms in PTEN and primary ovarian insufficiency in a Han Chinese population

SNP Alleles Associated allele HWE cases HWE controls MAF cases (n = 148) MAF controls (n = 230) OR 95 % CI Value p Bonferroni correction
rs1234219 T/C C 0.95 0.72 0.084 0.084 1.010 0.596–1.711 0.001 0.971 1.000
rs1903858 C/T C 0.60 0.90 0.446 0.509 0.777 0.579–1.043 2.834 0.092 0.644
rs2299939 C/A C 0.45 0.16 0.146 0.206 0.661 0.445–0.982 4.230 0.040 0.280
rs35352882 T/C C 0.58 0.51 0.044 0.042 1.047 0.509–2.153 0.015 0.901 1.000
rs17107001 G/T T 0.64 0.63 0.037 0.031 1.208 0.541–2.697 0.212 0.645 1.000
rs2299941 A/G G 0.68 0.62 0.378 0.354 1.111 0.820–1.505 0.460 0.498 1.000
rs12572106 T/C C 0.74 0.44 0.443 0.389 1.245 0.925–1.676 2.091 0.148 1.000
  1. The allele frequencies were performed with Pearson’s chi-squared test or Fisher’s exact test using SPSS 13.0 software. The allele frequencies of rs2299939 showed no significant difference after Bonferroni correction between POI patients and the controls