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Table 2 E2 concentrations measured with the E2 reagent and iE2 reagent according to largest follicle size

From: Changes in estrone and estradiol levels during follicle development: a retrospective large-scale study

Diameter of the largest follicle Serum E2 (pg/mL)
Age <38 year (n = 4032) Age 38–40 year (n = 3740) Age >40 year (n = 6599)
11 mm E2 reagent (n = 125) 99.9 ± 32.6a E2 reagent (n = 99) 101.5 ± 30.9a E2 reagent (n = 195) 113.4 ± 45.3a
iE2 reagent (n = 191) 68.0 ± 34.7a iE2 reagent (n = 147) 71.0 ± 40.4a iE2 reagent (n = 220) 86.8 ± 51.8a
12 mm E2 reagent (n = 114) 105.8 ± 35.6a E2 reagent (n = 122) 113.5 ± 40.9a E2 reagent (n = 226) 125.3 ± 48.2a
iE2 reagent (n = 234) 80.4 ± 41.8a iE2 reagent (n = 177) 84.7 ± 42.9a iE2 reagent (n = 297) 102.8 ± 53.5a
13 mm E2 reagent (n = 127) 122.2 ± 44.6a E2 reagent (n = 114) 135.9 ± 49.0a E2 reagent (n = 242) 142.2 ± 49.1a
iE2 reagent (n = 241) 87.3 ± 42.6a iE2 reagent (n = 200) 96.7 ± 44.6a iE2 reagent (n = 284) 116.1 ± 61.2a
14 mm E2 reagent (n = 125) 130.7 ± 38.8a E2 reagent (n = 125) 155.2 ± 57.4a E2 reagent (n = 234) 166.6 ± 59.8a
iE2 reagent (n = 246) 100.3 ± 51.7a iE2 reagent (n = 182) 115.8 ± 58.6a iE2 reagent (n = 313) 126.1 ± 64.0a
15 mm E2 reagent (n = 118) 168.0 ± 57.0a E2 reagent (n = 154) 168.8 ± 60.2a E2 reagent (n = 313) 187.0 ± 70.6a
iE2 reagent (n = 268) 132.6 ± 64.2a iE2 reagent (n = 238) 150.2 ± 66.5a iE2 reagent (n = 407) 170.6 ± 76.5a
16 mm E2 reagent (n = 134) 186.7 ± 67.8a E2 reagent (n = 173) 195.4 ± 60.0a E2 reagent (n = 351) 210.4 ± 64.6
iE2 reagent (n = 287) 160.0 ± 77.9a iE2 reagent (n = 222) 177.0 ± 78.2a iE2 reagent (n = 444) 197.4 ± 79.5
17 mm E2 reagent (n = 151) 228.5 ± 66.2a E2 reagent (n = 158) 236.6 ± 64.0a E2 reagent (n = 351) 231.8 ± 61.1
iE2 reagent (n = 322) 200.2 ± 85.7a iE2 reagent (n = 282) 216.5 ± 78.5a iE2 reagent (n = 489) 222.3 ± 86.6
18 mm E2 reagent (n = 151) 241.0 ± 75.0 E2 reagent (n = 143) 257.3 ± 60.9a E2 reagent (n = 348) 255.9 ± 59.2
iE2 reagent (n = 323) 229.2 ± 85.4 iE2 reagent (n = 356) 233.5 ± 88.9a iE2 reagent (n = 529) 247.0 ± 82.2
19 mm E2 reagent (n = 102) 253.4 ± 66.1 E2 reagent (n = 112) 260.8 ± 68.2 E2 reagent (n = 230) 259.2 ± 64.6
iE2 reagent (n = 242) 249.6 ± 78.0 iE2 reagent (n = 273) 256.0 ± 79.5 iE2 reagent (n = 368) 261.0 ± 83.5
20 mm E2 reagent (n = 109) 275.2 ± 72.2 E2 reagent (n = 107) 279.9 ± 75.1 E2 reagent (n = 230) 281.5 ± 74.2
iE2 reagent (n = 422) 275.6 ± 95.2 iE2 reagent (n = 356) 285.1 ± 88.0 iE2 reagent (n = 528) 280.6 ± 92.0
  1. Data are presented as mean ± standard deviation
  2. aSignificant differences in serum E2 concentration were found between measurements performed using the ST AIA-PACK E2 reagent and the ST AIA-PACK iE2 reagent (P <0.01)
  3. E2 estradiol, E2 reagent ST AIA-PACK E2 reagent, iE2 reagent ST AIA-PACK iE2 reagent