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Table 3 Allele and genotype analysis of rs9939609 and rs17782313

From: Interaction between common variants of FTO and MC4R is associated with risk of PCOS

SNP

Comparisons

PCOS

Control

P

OR (95 % CI)

Minor/Major

Minor/Major

rs9939609 A/T

ADD

16/153/564

7/168/717

0.030

-

 

DOM

169/564

175/717

0.091

1.23 (0.97–1.56)

 

REC

16/717

7/885

0.020

2.82 (1.15–6.89)

rs17782313 C/T

ADD

35/285/413

27/354/511

0.187

-

 

DOM

320/413

381/511

0.70

1.04 (0.85–1.27)

 

REC

35/698

27/865

0.067

1.61 (0.96–2.68)

  1. ADD additive genotype (three genotypes) study, DOM dominant genotype (homozygotes of risk allele + heterozygotes vs. homozygotes of non-risk allele) study, REC recessive genotype study (homozygotes of risk allele vs. heterozygotes + homozygotes of non-risk allele)