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Table 2 Genes regulated by progesterone after 2 h in mouse fallopian tubes

From: Progesterone-mediated effects on gene expression and oocyte-cumulus complex transport in the mouse fallopian tube

Gene symbol

Gene name

Selected GO-terms (Biological Process)

Fold-change

Serpina3n

Serpin Peptidase Inhibitor, Clade A, member 3

Response to peptide hormone

1.4

Edn1

Endothelin-1

Intracellular signaling cascade, Maternal process involved in parturition, Positive regulation of smooth muscle contraction

1.3

Rasd1

RAS, dexamethasone-induced 1

Intracellular signaling cascade, nitric oxide mediated signal transduction, small GTPase mediated signal transduction

1.4

Slc25a33

Solute carrier family 25 member 33

Small molecule transport

1.6

Tigd2

Tigger transposable element-derived protein 2

DNA binding

1.9

Arfl4

ADP-ribosylation factor like 4D

Intracellular signaling cascade

1.9

Irak2

Interleukin-1 receptor associated kinase 2

Intracellular signaling cascade

1.3

Cxcl1

chemokine (C-X-C motif) ligand 1

Positive regulation of cytosolic calcium ion concentration

1.4

Glrx

Glutaredoxin

AtPase binding

1.9

Amigo2

Adhesion molecule with ig like domain 2

Cell adhesion, negative regulation of programmed cell death

1.3

P4HA2

Prolyl 4 hydroxylase alpha polypeptide II

Oxidation-reduction process

1.3

  1. Mice fallopian tubes were treated in vitro with progesterone (100 nmol/L) or vehicle for 2 h and analysed by microarray. Eleven genes were differentially expressed (q-value ≤20 %). The fold-change refers to progesterone versus vehicle-treated fallopian tubes. A positive value indicates up-regulation by progesterone.