Type of disorder | Disorder | Age (Reference age) | Relative risk | Reference |
---|---|---|---|---|
Neuro-cognitive | Autism | >45(<20) | 3.3 | [205] |
>50(<30) | 5.75 | [226] | ||
>50(<29) | 2.2 | |||
Bipolar disorder | >55(20–24) | 1.34 | [219] | |
Not specified | 1.20 | [220] | ||
>45(20–24) | 24.7 (Hazard Ratio) | |||
Schizophrenia | Not specified | 1.47 | [207] | |
Autosomal dominant |  | >50(25–29) | 1.66 | |
 | >32(<28) | 3.00 | [13] | |
 | >55(25) | 5.92 | ||
Achondroplasia | >30(<30) | 3.48 | [234] | |
 | >50(25–29) | 7.80 | [236] | |
Apert syndrome | - | - | ||
Neurofibromatosis I | >35 (<35) | 1.69 | [238] | |
 | >40(<30) | 2.9 | [239] | |
Osteogenesis imperfecta | 22-80 | 1.37 | [13] | |
 | >35(<35) | 1.62 | [240] | |
 | >35(<25) | - | - | |
Retinoblastoma | >35(Not specified) | 1.73 | [241] | |
 | >45 | 3.00 | [242] | |
Congenital Abnormalities | Cleft Lips | Not specified | Â | [243] |
Anencephaly | >40 | Â | [11] | |
Transposition of Great Vessels | >45 > 40 | 1.27 | [11] | |
1.20 | Â | |||
Ventricular Septal Defects | >35 | 3.63 | [160] | |
30–34 | 1.69 |  | ||
(25–29) |  |  | ||
Artrial Septal Defect | 35-39 | 1.95 | [160] | |
(25–29) | 1.2 |  | ||
40–44 |  |  | ||
(25–29) |  | |||
Neural tube defect | 45-49 | 1.3 | [160] | |
(25–29) |  | |||
 | >50(25–29) | 1.6 | [160] | |
 | 35-39 | 0.6 | ||
 | (20–29) |  |  | |
 | >50(25-29 | 2.3 | ||
MSA | >35(30–34) | 1.33 | [246] | |
Tracheoesophageal fistula | 30-34(<25) | 2.55 | [247] | |
- | 3.12 | [248] | ||
- | 1.34 | [248] | ||
Others | OCD | >40 | 1.14 | [248] |
Childhood CNS Tumor | >35-39 | 1.11 | [248] | |
(25–29) |  |  | ||
Childhood Leukemia | >35-39 | 1.29 | [248] | |
(25–29) |  |  | ||
Mood disorder | >35-39 | 1.07 | [249] | |
(25–29) |  |  | ||
Personality disorder | -- | - | [249] | |
Mental retardation | - | - | [249] | |
Pervasive developmental disorders | - | - | [249] |