Table 3 Differentially expressed proteins (DEP) participating in various biological processes
From: Major protein alterations in spermatozoa from infertile men with unilateral varicocele
GO molecular functional terms | Percentage of genes | GO term usage in gene list |
|---|---|---|
Small molecule metabolic process | 43.73 | 157/359 |
Cellular nitrogen compound metabolic process | 39.00 | 140/359 |
Response to stress | 32.87 | 118/359 |
Biosynthetic process | 31.20 | 112/359 |
Catabolic process | 31.20 | 112/359 |
Signal transduction | 29.25 | 105/359 |
Transport | 27.02 | 97/359 |
Anatomical structure development | 22.84 | 82/359 |
Immune | 22.84 | 82/359 |
Cell death | 21.17 | 76/359 |
Cellular protein modification process | 20.33 | 73/359 |
Cell differentiation | 16.16 | 58/359 |
Cell cycle | 15.04 | 54/359 |
Cellular amino acid metabolic process | 14.48 | 52/359 |
Cellular component assembly | 14.21 | 51/359 |
Symbiosis, encompassing mutualism through parasitism | 13.93 | 50/359 |
Generation of precursor metabolites and energy | 13.09 | 47/359 |
Carbohydrate metabolic process | 12.81 | 46/359 |
Homeostatic process | 11.98 | 43/359 |
Macromolecular complex assembly | 11.42 | 41/359 |
Lipid metabolic process | 11.14 | 40/359 |
Locomotion | 10.58 | 38/359 |
Reproduction | 10.58 | 38/359 |
Protein complex assembly | 10.31 | 37/359 |
Cell proliferation | 9.75 | 35/359 |
Membrane organization | 9.47 | 34/359 |
Cell motility | 8.91 | 32/359 |
Transmembrane transport | 8.36 | 30/359 |
Vesicle-mediated transport | 8.08 | 29/359 |
Nucleobase-containing compound catabolic process | 7.80 | 28/359 |
Protein folding | 6.96 | 25/359 |
Growth | 6.41 | 23/359 |
Protein targeting | 5.85 | 21/359 |
Cell adhesion | 5.85 | 21/359 |
Translation | 5.85 | 21/359 |
Cofactor metabolic process | 5.85 | 21/359 |
Anatomical structure formation involved in morphogenesis | 5.85 | 21/359 |
Neurological system process | 5.57 | 20/359 |
Cell morphogenesis | 5.57 | 20/359 |
Cell-cell signaling | 5.57 | 20/359 |
Circulatory system process | 4.74 | 17/359 |
Mitochondrion organization | 4.46 | 16/359 |
DNA metabolic process | 4.18 | 15/359 |
Cytoskeleton organization | 4.18 | 15/359 |
Embryo development | 3.90 | 14/359 |
Nucleocytoplasmic transport | 3.62 | 13/359 |
Sulfur compound metabolic process | 3.34 | 12/359 |
Protein maturation | 2.79 | 10/359 |
Aging | 2.51 | 9/359 |
Cell division | 2.51 | 9/359 |
Extracellular matrix organization | 2.23 | 8/359 |
tRNA metabolic process | 1.95 | 7/359 |
Chromosome organization | 1.95 | 7/359 |
Cell junction organization | 1.67 | 6/359 |
Mitosis | 1.39 | 5/359 |
Ribosome biogenesis | 1.39 | 5/359 |
Developmental maturation | 1.11 | 4/359 |
mRNA processing | 1.11 | 4/359 |
Ribonucleoprotein complex assembly | 0.84 | 3/359 |
Cytoskeleton-dependent intracellular transport | 0.84 | 3/359 |
Plasma membrane organization | 0.56 | 2/359 |
Cell wall organization or biogenesis | 0.28 | 1/359 |
Nitrogen cycle metabolic process | 0.28 | 1/359 |
Chromosome segregation | 0.28 | 1/359 |
Pigmentation | 0.28 | 1/359 |