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Table 2 Differentially expressed proteins (DEP) participating in various cellular molecular functions

From: Major protein alterations in spermatozoa from infertile men with unilateral varicocele

GO biological process terms

Percentage of genes

GO term usage in gene list

Ion binding

44.85

161/359

Oxidoreductase activity

13.65

49/359

Peptidase activity

13.09

47/359

Enzyme binding

11.14

40/359

Enzyme regulator activity

8.36

30/359

RNA binding

6.69

24 of 359

Structural molecule activity

5.85

21/359

Unfolded protein binding

5.29

19/359

Lipid binding

5.01

18/359

DNA binding

4.46

16/359

ATPase activity

3.90

14/359

Cytoskeletal protein binding

3.62

13/359

Transmembrane transporter activity

3.62

13/359

Ligase activity

2.79

10/359

Kinase activity

2.79

10/359

Isomerase activity

2.79

10/359

Phosphatase activity

2.51

9/359

Transferase activity, transferring acyl groups

2.51

9/359

Lyase activity

2.23

8/359

Hydrolase activity, acting on carbon-nitrogen bonds

2.23

8/359

Structural constituent of ribosome

1.67

6/359

Hydrolase activity, acting on glycosyl bonds

1.67

6/359

Protein binding transcription factor activity

1.67

6/359

Signal transducer activity

1.39

5/359

GTPase activity

1.39

5/359

mRNA binding

1.11

4/359

Nucleic acid binding transcription factor activity

1.11

4/359

Protein transporter activity

1.11

4/359

Transferase activity, transferring glycosyl groups

1.11

4/359

Translation factor activity, nucleic acid binding

0.84

3/359

Nuclease activity

0.84

3/359

Transcription factor binding

0.84

3/359

Small conjugating protein binding

0.56

2/359

Protein binding, bridging

0.56

2/359

Helicase activity

0.56

2/359

Transferase activity, transferring alkyl or aryl groups

0.28

1/359

rRNA binding

0.28

1/359

  1. Note: Of the 369 differentially expressed proteins (DEP), only 359 are involved in the pathways according to the Gene Ontology mapper.