FGF21 in PE. A) Placental mRNA expression of FGF21 in 20 control women (white circles) and 17 women with PE (grey squares). B) Placental protein expression of FGF21 in 11 control women (white boxes) and 9 women with PE (grey boxes), inset representative picture of western blot with FGF21 in green and B-actin in red. C) Serum levels of FGF21 of in maternal and cord blood of 10 control women (white circles and white squares respectively) and 10 with PE (grey circles and grey squares respectively). Representative immunohistochemistry of FGF21 in placenta from control women (D), women with PE (E) and no primary antibody negative control (F). Line is median and IQR in A and B; *, P < 0.05.