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Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis

Figure 2

Diagrams depicting interactions between six of the seven aromatase-inhibiting AEDs, oxcarbazepine (DB #776) not included, since information about its interactions was unavailable. Specific molecule types are represented as: cytokines (square), growth factors (dotted square), small molecule drugs or toxicants (oval), enzymes (vertical diamond), G-protein coupled receptors (vertical rectangle), ion channels (dotted vertical rectangle), kinases (inverted traingle), ligand-dependent nuclear receptors (rectangle), peptidases (horizontal diamond), phosphatases (triangle), transcription regulators (horizontal ellipse), translation regulators (hexagon), transmembrane receptors (vertical ellipse), transporters (trapezoid), microRNA (inverted trapezoid), complexes (thick circle), and other important molecules (circle). Dotted lines indicate an indirect interaction, while solid lines indicate a direct interaction.

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