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Table 2 Adverse effects of treatment experienced by patients included in the study

From: Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial

Adverse effect

group T

(n = 18)

group N

(n = 17)

p

Arthralgia

7 (38.9%)

1 (5.9%)

0.041

Myalgia

3 (16.7%)

1 (5.9%)

0.603

Persistent breakthrough bleeding

0 (0.0%)

2 (11.8%)

0.229

Depression

4 (22.2%)

1 (5.9%)

0.338

Insomnia

3 (16.7%)

0 (0.0%)

0.229

Decreased libido

4 (22.2%)

2 (11.8%)

0.658

Vaginal dryness

3 (16.7%)

0 (0.0%)

0.229

Hot flushes

4 (22.2%)

0 (0.0%)

0.104

Hair loss

2 (11.1%)

0 (0.0%)

0.486

Headache

2 (11.1%)

0 (0.0%)

0.486

Weight gain

1 (5.6%)

2 (11.8%)

0.603

At least one adverse effect

14 (77.8%)

6 (35.3%)

0.018