Table 1 RCTs comparing letrozole versus clomiphene as first line for anovulatory women
From: Letrozole or clomiphene citrate as first line for anovulatory infertility: a debate
Sl no | Authors | Study design | Treatment arms | Numbers cycles | Endometrial thickness (mm) | Ovulation rates (%) | Pregnancy rates (%) |
|---|---|---|---|---|---|---|---|
1 | Atay V et al. [9] Turkey, 2006 | RCT | Letrozole 2.5 mg vs. Clomiphene 100 mg | 51 vs. 55 | 8.4 +/- 1.8 vs. 5.2 +/- 1.2 | 82.4 vs. 63.6 | 21.6 vs. 9.1 |
2 | Bayar U et al. [10] Turkey, 2006 | RCT | Letrozole 2.5 mg vs. Clomiphene 100 mg | 99 vs. 95 | 8# vs. 8# | 65.7 vs. 74.7 | 9.1 vs. 7.4 |
3 | Badawy A et al. [11] Egypt, 2009 | RCT | Letrozole 5 mg vs. Clomiphene 100 mg | 540 vs. 523 | 8.1+/-0.2 vs. 9.2+/-0.7 | 67.5 vs. 70.9 | 15.1 vs. 17.9 |