Skip to main content

Table 2 Available randomized trials regarding the use of letrozole during the luteal phase in oocyte donors

From: Aromatase inhibitors in stimulated IVF cycles

  Luteal phase supplementation Days of administration Patients (N) Serum estradiol levels (mean values) LH levels (mean values)
LUTEAL PHASE     Day 4 Day 7 Day 10 Day 4 Day 7 Day 10
   Fatemi 2008 [14] Letrozole 5 mg For 14 days from OPU 3 272 229 31 0.2 0.1 0.1
  Placebo   3 749 1457 1308 0.2 0.1 0.1
   Garcia-Velasco 2009 [15] Letrozole 2.5 mg For 5 days from OPU 15 279 240 40 0.21 0.18 0.40
  Placebo (folic acid)   15 1586 855 448 0.06 0.02 0.16
  1. OPU, ovum pick-up