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Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: Persistence of decidual NK cells and KIR genotypes in healthy pregnant and preeclamptic women: a case-control study in the third trimester of gestation

Figure 2

KIR genotype distribution in control and preeclamptic women. KIR genotype distribution and percentage (%) of women displaying each genotype in healthy women (Controls) and women with preeclampsia (PE). Shaded boxes represent the presence of the inhibitory genes (2DL1, 2DL2, 2DL3, 2DL4, 2DL5all, 2DL5A, 2DL5B, 3DL1, 3DL2, 3DL3), activating (2DS1, 2DS2, 2DS3, 2DS4 del, 2DS4 ins, 2DS5, 3DS1) and pseudogenes (2DP1, 3DP1). White boxes indicate the absence of KIR gene. Dark boxes indicate the presence of KIR gene. Dashed boxes indicate that the genotype was assigned when either 2DS4 ins and 2DS4 del variants were detected. The total number of KIR genes in each genotype is indicated, as well as the numbers of activating (S) and inhibitory (L) genes. Ratios of the activating to inhibitory genes are showed in the right column. The p values less than 0.05 were corrected for 57 comparisons using the Bonferroni correction. a p = 0.012, OR = 0.067, 95% IC 0.004 to 1.204; pc > 0.05 b p = 0.03, OR = 0.124, 95% IC 0.015 to 1.028; pc > 0.05

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