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Table 6 Summary and projected pregnancy rate compensating for the double counting of pregnancies in case a subject has more than one pregnancy

From: Should a single blastocyst transfer policy be a clinical decision or should it depend on the embryological evaluation on day 3?

  eSET with elective day 5 transfer eSET with transfer day 3 or 5 Statistical significance
No. of fresh cycles 341 249  
No. of thawed cycles 188 143  
Subjects with fresh or thawed clinical pregnancy 147 100  
Subjects with fresh or thawed ongoing pregnancy 142 91  
Number of embryos unthawed1 38 98  
Clinical pregnancy rate thawed embryos 26/286 (9.09) 21/229 (9.17) NS
Ongoing pregnancy rate thawed embryos 24/286 (8.39) 18/229 (7.86) NS
Projected number subjects with clinical pregnancy2 3.45 9.68 (1.24+8.44)  
Projected number subjects with a ongoing pregnancy2 3.19 8.20 (1.24+6.96)  
Projected cumulative clinical pregnancy rate3 150.45/341 (44.12) 109.68/249 (44.04) NS
Projected cumulative ongoing pregnancy rate3 145.19/341 (42.58) 99.20/249 (39.84) NS
   Day 3 Day 5  
No. of fresh cycles   135 102  
No. of thawed cycles   41 102  
Subjects with fresh or thawed clinical pregnancy   43 57  
Subjects with fresh or thawed ongoing pregnancy   40 51  
Number of embryos unthawed2   26 72  
Clinical pregnancy rate thawed embryos   4/84 (4.76) 17/145 (11.72) NS
Ongoing pregnancy rate thawed embryos   4/84 (4.76) 14/145 (9.66) NS
Projected number subjects with clinical pregnancy   1.24 8.44  
Projected number subjects with a ongoing pregnancy   1.24 6.96  
  1. 1 Number of embryos unthawed for subjects with no fresh or thawed pregnancy
  2. 2 Projected from the unthawed material among subjects without a fresh or thawed pregnancy, assuming that the pregnancy rate will be the same as for the already thawed material
  3. 3 Fresh pregnancies, thawed pregnancies and projected number of pregnancies/number of subjects